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    • Parp1 protects against Aag-dependent alkylation-induced nephrotoxicity in a sex-dependent manner 

      Calvo, Jennifer A.; Allocca, Mariacarmela; Fake, Kimberly R.; Muthupalani, Sureshkumar; Corrigan, Joshua J.; Bronson, Roderick T.; Samson, Leona D. (Impact Journals LLC, 2016)
      Nephrotoxicity is a common toxic side-effect of chemotherapeutic alkylating agents. Although the base excision repair (BER) pathway is essential in repairing DNA alkylation damage, under certain conditions the initiation ...