Browsing by Keyword "B-cell tolerance"
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The site of allergen expression in hematopoietic cells determines the degree and quality of tolerance induced through molecular chimerism
(Blackwell Publishing Ltd, 2013)The transplantation of allergens (e.g. Phl p 5 or Bet v 1) expressed on BM cells as membrane-anchored full-length proteins leads to permanent tolerance at the T-cell, B-cell, and effector-cell levels. Since the exposure ...