Browsing by Keyword "Cytokine"
Now showing items 1-3 of 3
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Bayesian modeling suggests that IL-12 (p40), IL-13 and MCP-1 drive murine cytokine networks in vivo
(BioMed Central, 2015)Background: Cytokine-hormone network deregulations underpin pathologies ranging from autoimmune disorders to cancer, but our understanding of these networks in physiological/pathophysiological states remains patchy. We ... -
CBL and the Negative Regulation of Cytokine Receptor Signaling
(2020-11-23)Cytokines play an essential role in the growth, differentiation, and effector functions of hematopoietic cells. The control of cytokine-mediated signaling is critical to maintaining both cellular- and organismal-level ... -
A critical role for suppressors of cytokine signaling 3 in regulating LPS-induced transcriptional activation of matrix metalloproteinase-13 in osteoblasts
(PeerJ Inc., 2013)Suppressor of cytokine signaling 3 (SOCS3) is a key regulator of cytokine signaling in macrophages and T cells. Although SOCS3 seems to contribute to the balance between the pro-inflammatory actions of IL-6 family of ...