Browsing by Keyword "E2F"
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GATA1s induces hyperproliferation of eosinophil precursors in Down syndrome transient leukemia
(2014)Transient leukemia (TL) is evident in 5–10% of all neonates with Down syndrome (DS) and associated with N-terminal truncating GATA1-mutations (GATA1s). Here we report that TL cell clones generate abundant eosinophils in a ...