Browsing by Keyword "Pin1"

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    • Death-associated protein kinase 1 has a critical role in aberrant tau protein regulation and function 

      Kim, B M; You, M-H; Chen, C-H; Lee, S; Hong, Y; Kimchi, A; Zhou, X Z; Lee, T H (Nature Publishing Group, 2014)
      The presence of tangles composed of phosphorylated tau is one of the neuropathological hallmarks of Alzheimer's disease (AD). Tau, a microtubule (MT)-associated protein, accumulates in AD potentially as a result of ...

    • The Prolyl Isomerase Pin1 in Breast Development and Cancer 

      Wulf, Gerburg Maria; Ryo, Akihide; Liou, Yih-Cherng; Lu, Kun Ping (BioMed Central, 2003)
      The prolyl isomerase Pin1 specifically isomerizes certain phosphorylated Ser/Thr-Pro bonds and thereby regulates various cellular processes. Pin1 is a target of several oncogenic pathways and is overexpressed in human ...