Browsing by Keyword "Pneumococcus"

Now showing items 1-3 of 3

    • Identification of Protective Pneumococcal \(T_{H}17\) Antigens from the Soluble Fraction of a Killed Whole Cell Vaccine 

      Moffitt, Kristin Leigh; Malley, Richard; Lu, Ying-Jie (Public Library of Science, 2012)
      Mucosal or parenteral immunization with a killed unencapsulated pneumococcal whole cell antigen (WCA) with an adjuvant protects mice from colonization by a \(T_{H}17\) CD4+ cell-mediated mechanism. Using preparative SDS ...

    • The Lectin Pathway of Complement Activation Is a Critical Component of the Innate Immune Response to Pneumococcal Infection 

      Ali, Youssif M.; Lynch, Nicholas J.; Haleem, Kashif S.; Fujita, Teizo; Endo, Yuichi; Hansen, Soren; Holmskov, Uffe; Takahashi, Kazue; Stahl, Gregory L.; Dudler, Thomas; Girija, Umakhanth V.; Wallis, Russell; Kadioglu, Aras; Stover, Cordula M.; Andrew, Peter W.; Schwaeble, Wilhelm J. (Public Library of Science, 2012)
      The complement system plays a key role in host defense against pneumococcal infection. Three different pathways, the classical, alternative and lectin pathways, mediate complement activation. While there is limited information ...

    • Streptococcus pneumoniae Carriage in the Gaza Strip 

      Shainberg, Bracha; Varon, Miriam; Roytman, Yulia; Ziv, Arnona; Goral, Aviva; Elhamdany, Abedallah; Rahav, Galia; Raz, Meir; Regev-Yochay, Gili; Abullaish, Izzeldin; Malley, Richard (Public Library of Science, 2012)
      Background: Pneumococcal infections cause major morbidity and mortality in developing countries. We report the epidemiology of S. pneumoniae carriage in a developing region, the Gaza strip, and evaluate the theoretical ...