Browsing by Keyword "S1"

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    • Impact of oncogenic driver mutations on feedback between the PI3K and MEK pathways in cancer cells 

      Yuen, Hiu-Fung; Abramczyk, Olga; Montgomery, Grant; Chan, Ka-Kui; Huang, Yu-Han; Sasazuki, Takehiko; Shirasawa, Senji; Gopesh, Srivastava; Chan, Kwok-Wah; Fennell, Dean; El-Tanani, Mohamed; Janne, Pasi Antero; Murray, James T. (Portland Press Ltd., 2012)
      Inhibition of the PI3K (phosphoinositide 3-kinase)/Akt/mTORC1 (mammalian target of rapamycin complex 1) and Ras/MEK [MAPK (mitogen-activated protein kinase)/ERK (extracellular-signal-regulated kinase) kinase]/ERK pathways ...