Browsing by Keyword "T cell receptor, epitope spreading, melanoma"

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Personal Neoantigen Vaccines Induce Persistent Neoantigen-Specific Memory T Cell Responses and Epitope Spreading in High-Risk Melanoma Patients

Leet, Donna (2020-06-24)

Cancer vaccines have long been envisioned as an effective approach to generate, amplify and diversify T cell responses against tumors. The recent availability of next-generation sequencing (NGS) has enabled the comprehensive ...