Now showing items 1-4 of 4

    • Coordination of Individual and Ensemble Cytoskeletal Motors Studied Using Tools from DNA Nanotechnology 

      Derr, Nathan Dickson (2013-09-30)
      The cytoskeletal molecular motors kinesin-1 and cytoplasmic dynein drive many diverse functions within eukaryotic cells. They are responsible for numerous spatially and temporally dependent intracellular processes crucial ...
    • Investigating Cytoskeletal Motor Mechanisms using DNA Nanotechnology 

      Goodman, Brian Kruzick (2014-02-25)
      The microtubule cytoskeleton plays a vital role in the spatial-temporal organization of subcellular cargo required to maintain homeostasis and direct cell division. Cytoplasmic dynein and kinesin are opposite-polarity, ...
    • Mechanisms of Regulation of Cytoplasmic Dynein 

      Htet, Zaw Min (2019-04-29)
      Cytoplasmic dynein-1 (dynein) is a microtubule-based motor protein that is essential for maintaining proper spatial and temporal organization of the cellular interior during both interphase and cell division. To do so, ...
    • Microtubule Motors Power Plasma Membrane Tubulation in Clathrin-Independent Endocytosis 

      Day, Charles A.; Baetz, Nicholas W.; Copeland, Courtney A.; Kraft, Lewis J.; Han, Bing; Tiwari, Ajit; Drake, Kimberly R.; De Luca, Heidi; Chinnapen, Daniel J.-F.; Davidson, Michael W.; Holmes, Randall K.; Jobling, Michael G.; Schroer, Trina A.; Lencer, Wayne I.; Kenworthy, Anne K. (2015)
      How the plasma membrane is bent to accommodate clathrin-independent endocytosis remains uncertain. Recent studies suggest Shiga and cholera toxin induce membrane curvature required for their uptake into clathrin-independent ...