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    • Altered mechanobiology of Schlemm's canal endothelial cells in glaucoma 

      Overby, Darryl R.; Zhou, Enhua; Vargas-Pinto, Rocio; Pedrigi, Ryan M.; Fuchshofer, Rudolf; Braakman, Sietse T.; Gupta, Ritika; Perkumas, Kristin M.; Sherwood, Joseph M.; Vahabikashi, Amir; Dang, Quynh Nhu; Kim, Jae Hun; Ethier, C. Ross; Stamer, W. Daniel; Fredberg, Jeffrey J.; Johnson, Mark (Proceedings of the National Academy of Sciences, 2014)
      Increased flow resistance is responsible for the elevated intraocular pressure characteristic of glaucoma, but the cause of this resistance increase is not known. We tested the hypothesis that altered biomechanical behavior ...