Now showing items 1-3 of 3

    • Engineered stem cells releasing oncolytic virus and immunomodulators have therapeutic efficacy in brain metastatic tumors 

      seddiq, waleed (2023-05-11)
      Background: Brain metastasis is common among patients with advanced lung cancer and melanoma and is associated with significant morbidity and mortality. Conventional treatments, such as surgery, radiation, and chemotherapy, ...
    • Gene therapy on the move 

      Kaufmann, Kerstin B; Büning, Hildegard; Galy, Anne; Schambach, Axel; Grez, Manuel (Blackwell Publishing Ltd, 2013)
      The first gene therapy clinical trials were initiated more than two decades ago. In the early days, gene therapy shared the fate of many experimental medicine approaches and was impeded by the occurrence of severe side ...
    • Micro- and Nanoengineering Approaches to Control Stem Cell-Biomaterial Interactions 

      Dolatshahi-Pirouz, Alireza; Nikkhah, Mehdi; Kolind, Kristian; Dokmeci, Mehmet R.; Khademhosseini, Ali (MDPI, 2011)
      As our population ages, there is a greater need for a suitable supply of engineered tissues to address a range of debilitating ailments. Stem cell based therapies are envisioned to meet this emerging need. Despite significant ...