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    • CD4+ T cells mediate antibody-independent acquired immunity to pneumococcal colonization 

      Malley, Richard; Trzcinski, K.; Srivastava, Amit; Thompson, Claudette M.; Anderson, Porter; Lipsitch, Marc (Proceedings of the National Academy of Sciences, 2005)
      Acquired immunity to Streptococcus pneumoniae (pneumococcus) has long been assumed to depend on the presence of anticapsular antibodies. We found, however, that colonization with live pneumococci of serotypes 6B, 7F, or ...