(American Chemical Society (ACS), 2013) Mazzotti, Anthony Renato; Campbell, Michael Glenn; Tang, Pingping; Murphy, Jennifer; Ritter, Tobias
A practical, palladium-catalyzed synthesis of aryl fluorides from arylboronic acid derivatives is presented. The reaction is operationally simple and amenable to multigram-scale synthesis. Evaluation of the reaction mechanism suggests a single-electron-transfer pathway, involving a Pd(III) intermediate that has been isolated and characterized.
