Now showing items 1-3 of 3

    • Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence 

      Choi, Sekyu; Zhang, Bing; Ma, Sai; Gonzalez Celeiro, Meryem; Stein, Daniel; Jin, Xin; Kim, Seung Tea; Kang, Yuan-Lin; Besnard, Antoine; Rezza, Amelie; Grisanti, Laura; Buenrostro, Jason; Rendl, Michael; Nahrendorf, Matthias; Sahay, Amar; Hsu, Ya-chieh (Springer Science and Business Media LLC, 2021-03-31)
      Chronic, sustained exposure to stressors can profoundly impact tissue homeostasis, although the mechanisms by which these changes occur are largely unknown. Here, we report the adrenal gland-derived stress hormone ...
    • A microRNA expression and regulatory element activity atlas of the mouse immune system 

      Rose, Samuel A.; Wroblewska, Aleksandra; Dhainaut, Maxime; Yoshida, Hideyuki; Shaffer, Jonathan M.; Bektesevic, Anela; Ben-Zvi, Benjamin; Rhoads, Andrew; Kim, Edy Y.; Yu, Bingfei; Lavin, Yonit; Merad, Miriam; Buenrostro, Jason D.; Brown, Brian D.; Aguilar, Oscar; Allan, Rhys; Arakawa-Hoyt, Janice; Astarita, Jilian; Austen, K. Frank; Barrett, Nora; Baysoy, Alev; Benoist, Christophe; Buechler, Matthew; Buenrostro, Jason; Casanova, Maria Acebes; Choi, Kyunghee; Chowdhary, Kaitavjeet; Colonna, Marco; Crowl, Ty; Deng, Tianda; Desai, Jigar V.; Desland, Fiona; Ding, Jiarui; Dominguez, Claudia; Dwyer, Daniel; Frascoli, Michela; Gal-Oz, Shani; Goldrath, Ananda; Grieshaber-Bouyer, Ricardo; Jia, Baosen; Johanson, Tim; Jordan, Stefan; Kang, Joonsoo; Kapoor, Varun; Kenigsberg, Ephraim; Kim, Joel; Kim, Ki wook; Kiner, Evgeny; Kronenberg, Mitchell; Lanier, Lewis; Laplace, Catherine; Lareau, Caleb; Leader, Andrew; Lee, Jisu; Magen, Assaf; Maier, Barbara; Maslova, Alexandra; Mathis, Diane; McFarland, Adelle; Meunier, Etienne; Monach, Paul; Mostafavi, Sara; Muller, Soren; Muus, Christoph; Ner-Gaon, Hadas; Nguyen, Quyhn; Nigrovic, Peter A.; Niizuma, Kouta; Novakovsky, German; Nutt, Stephen; Omilusik, Kayla; Ortiz-Lopez, Adriana; Paynich, Mallory; Peng, Vincent; Potempa, Marc; Pradhan, Rachana; Quon, Sara; Ramirez, Ricardo; Ramanan, Deepshika; Randolph, Gwendalyn; Regev, Aviv; Seddu, Kumba; Shay, Tal; Shemesh, Avishai; Shyer, Justin; Smilie, Christopher; Spidale, Nick; Subramanian, Ayshwarya; Sylvia, Katelyn; Tellier, Julie; Turley, Shannon; Vijaykumar, Brinda; Wagers, Amy; Wang, Chendi; Wang, Peter L.; Yang, Liang; Yim, Aldrin (Springer Science and Business Media LLC, 2021-06-07)
      microRNAs (miRNA) play an important role in immune system development and function, often participating in regulatory networks with the transcription factors that drive their expression. However, many of these relationships ...
    • Single-cell epigenomic variability reveals functional cancer heterogeneity 

      Litzenburger, Ulrike M.; Buenrostro, Jason D.; Wu, Beijing; Shen, Ying; Sheffield, Nathan C.; Kathiria, Arwa; Greenleaf, William J.; Chang, Howard Y. (BioMed Central, 2017)
      Background: Cell-to-cell heterogeneity is a major driver of cancer evolution, progression, and emergence of drug resistance. Epigenomic variation at the single-cell level can rapidly create cancer heterogeneity but is ...