Browsing Faculty of Arts and Sciences by Author "Raaijmakers, Marc H.G.P."

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    • Specific bone cells produce DLL4 to generate thymus-seeding progenitors from bone marrow 

      Yu, Vionnie W.C.; Saez, Borja; Cook, Colleen; Lotinun, Sutada; Pardo-Saganta, Ana; Wang, Ying-Hua; Lymperi, Stefania; Ferraro, Francesca; Raaijmakers, Marc H.G.P.; Wu, Joy Y.; Zhou, Lan; Rajagopal, Jayaraj; Kronenberg, Henry M.; Baron, Roland; Scadden, David T. (The Rockefeller University Press, 2015)
      Production of the cells that ultimately populate the thymus to generate α/β T cells has been controversial, and their molecular drivers remain undefined. Here, we report that specific deletion of bone-producing osteocalcin ...