Now showing items 41-60 of 1193

    • Anomalously Rapid Tunneling: Charge Transport across Self-Assembled Monolayers of Oligo(ethylene glycol) 

      Baghbanzadeh, Mostafa; Bowers, Carleen M.; Rappoport, Dmitrij; ?aba, Tomasz; Yuan, Li; Kang, Kyungtae; Liao, Kung-Ching; Gonidec, Mathieu; Rothemund, Philipp Josef Michael; Cyganik, Piotr; Aspuru-Guzik, Alan; Whitesides, George McClelland (American Chemical Society (ACS), 2017)
      This paper describes charge transport by tunneling across self-assembled monolayers (SAMs) of thiol-terminated derivatives of oligo(ethylene glycol) (HS(CH2CH2O)nCH3; HS(EG)nCH3); these SAMs are positioned between gold ...
    • Anti-Brownian Traps for Studies on Single Molecules 

      Fields, Alexander; Cohen, Adam Ezra (Elsevier BV, 2010)
      Until recently, Brownian motion was seen as an immutable feature of small particles in room-temperature liquids. Molecules, viruses, organelles, and small cells jiggle incessantly due to countless collisions with thermally ...
    • Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones 

      Maianti, Juan Pablo; McFedries, Amanda; Foda, Zachariah H.; Kleiner, Ralph; Du, Xiu Quan; Leissring, Malcolm A.; Tang, Wei-Jen; Charron, Maureen J.; Seeliger, Markus A.; Saghatelian, Alan; Liu, David Ruchien (Nature Publishing Group, 2014)
      Despite decades of speculation that inhibiting endogenous insulin degradation might treat type-2 diabetes, and the identification of IDE (insulin-degrading enzyme) as a diabetes susceptibility gene, the relationship between ...
    • An antibiotic binds to the ATPase that powers lipopolysaccharide transport 

      May, Janine Margaret (2016-07-05)
      The spread of antibiotic resistance has created an urgent need for new antibiotics. The situation is particularly serious for Gram-negative bacteria because they possess an outer membrane (OM) that prevents many antibiotics ...
    • Antilocalization of Coulomb Blockade in a Ge/Si Nanowire 

      Higginbotham, A; Kuemmeth, F; Larsen, T. W.; Fitzpatrick, M.; Yao, Jun; Yan, H.; Lieber, Charles M.; Marcus, C (American Physical Society (APS), 2014)
      The distribution of Coulomb blockade peak heights as a function of magnetic field is investigated experimentally in a Ge/Si nanowire quantum dot. Strong spin-orbit coupling in this hole-gas system leads to antilocalization ...
    • Antimony-doped Tin(II) Sulfide Thin Films 

      Sinsermsuksakul, Prasert; Chakraborty, Rupak; Kim, Sang Bok; Heald, Steven; Buonassisi, Tonio; Gordon, Roy Gerald (American Chemical Society, 2012-12-07)
      Thin-film solar cells made from earth-abundant, inexpensive, and nontoxic materials are needed to replace the current technologies whose widespread use is limited by their use of scarce, costly, and toxic elements. Tin ...
    • Application of a Catalytic Asymmetric Povarov Reaction using Chiral Ureas to the Synthesis of a Tetrahydroquinoline Library 

      Gerard, Baudouin; O’Shea, Morgan Welzel; Donckele, Etienne; Kesavan, Sarathy; Akella, Lakshmi B.; Xu, Hao; Jacobsen, Eric N.; Marcaurelle, Lisa A. (American Chemical Society, 2012)
      A 2328-membered library of 2,3,4-trisubstituted tetrahydroquinolines was produced using a combination of solution- and solid-phase synthesis techniques. A tetrahydroquinoline (THQ) scaffold was prepared via an asymmetric ...
    • Application of Compressed Sensing to the Simulation of Atomic Systems 

      Andrade, Xavier; Sanders, Jacob Nathan; Aspuru-Guzik, Alan (Proceedings of the National Academy of Sciences, 2012)
      Compressed sensing is a method that allows a significant reduction in the number of samples required for accurate measurements in many applications in experimental sciences and engineering. In this work, we show that ...
    • Application of Palladium-Mediated 18F-Fluorination to PET Radiotracer Development: Overcoming Hurdles to Translation 

      Kamlet, Adam; Neumann, Constanze Nicole; Lee, Eunsung; Carlin, Stephen M.; Moseley, Christian K.; Stephenson, Nickeisha A; Hooker, Jacob M; Ritter, Tobias (Public Library of Science, 2013)
      New chemistry methods for the synthesis of radiolabeled small molecules have the potential to impact clinical positron emission tomography (PET) imaging, if they can be successfully translated. However, progression of ...
    • Applications of sequence coevolution in membrane protein biochemistry 

      Nicoludis, John M.; Gaudet, Rachelle (Elsevier BV, 2018-04)
      Recently, protein sequence coevolution analysis has matured into a predictive powerhouse for protein structure and function. Direct methods, which use global statistical models of sequence coevolution, have enabled the ...
    • Aqueous Multiphase Systems of Polymers and Surfactants Provide Self-Assembling Step-Gradients in Density 

      Mace, Charles R.; Akbulut, Ozge; Kumar, Ashok Ashwin; Shapiro, Nathan D.; Derda, Ratmir; Patton, Matthew Reiser; Whitesides, George McClelland (American Chemical Society, 2012)
      This Communication demonstrates the generation of over 300 phase-separated systems—ranging from two to six phases—from mixtures of aqueous solutions of polymers and surfactants. These aqueous multiphase systems (MuPSs) ...
    • Arthrobots 

      Nemiroski, Alex; Shevchenko, Yanina Y.; Stokes, Adam A.; Unal, Baris; Ainla, Alar; Albert, Sahradha; Compton, Gabrielle; MacDonald, Emily; Schwab, Yosyp; Zellhofer, Caroline; Whitesides, George McClelland (Mary Ann Liebert Inc, 2017)
      This paper describes a class of robots—“arthrobots”— inspired, in part, by the musculoskeletal system of arthropods (spiders and insects, inter alia). An exoskeleton, constructed from thin organic polymeric tubes, provides ...
    • Assembly and integration of semiconductor nanowires for functional nanosystems 

      Yu, Guihua; Lieber, Charles M. (Walter de Gruyter GmbH, 2010)
      Central to the bottom-up paradigm of nanoscience, which could lead to entirely new and highly integrated functional nanosystems, is the development of effective assembly methods that enable hierarchical organization of ...
    • Assembly line termination in cylindrocyclophane biosynthesis: discovery of an editing type II thioesterase domain in a type I polyketide synthase 

      Nakamura, Hitomi; Wang, J; Balskus, Emily Patricia (Royal Society of Chemistry (RSC), 2015)
      The termination step is an important source of structural diversity in polyketide biosynthesis. Most type I polyketide synthase (PKS) assembly lines are terminated by a thioesterase (TE) domain located at the Cterminus of ...
    • Asymmetric Ion-Pairing Catalysis 

      Brak, Katrien; Jacobsen, Eric N. (Wiley Blackwell (John Wiley & Sons), 2013)
    • Atmospheric Chemistry and the Biosphere: General Discussion 

      Archibald, Alexander; Freedman, Arnold; Bejan, Lustian; Brown, Steven; Brüggemann, Martin; Carpenter, Lucy; Collins, John; Evans, Mathew; Finlayson-Pitts, Barbara; George, Christian; Hastings, Meredith; Heard, Dwayne; Hewitt, Christopher; Isaacman-VanWertz, Gabriel; Kalberer, Markus; Keutsch, Frank; Kiendler-Scharr, Astrid; Knopf, Daniel; Lelieveld, Jos; Marais, Eloise; Petzold, Andreas; Ravishankara, A.; Reid, Jonathan; Rovelli, Grazia; Scott, Catherine; Sherwen, Tomás; Shindell, Drew; Tinel, Liselotte; Unger, Nadine; Wallington, Timothy J.; Wahner, Andreas; Williams, Jonathan; Young, Timothy; Zelenyuk, Alla; Wallington, Timothy (Royal Society of Chemistry (RSC), 2017)
      Lucy Carpenter opened discussion of the paper by Christian George: Your previous work has emphasised the abiotic production of VOCs from surface ocean processes, mainly from photosensitized chemistry of surfactants. Does ...
    • Atomic layer depositied Indium oxy-sulfide on CZT(S,Se) absorbers 

      Jayaraman, Ashwin N Kr; Kim, Sang Bok; Gordon, Roy Gerald (2015)
    • Atomic Layer Deposition (ALD) and Chemical Vapor Deposition (CVD) of Copper-based Metallization for Microelectronic Fabrication 

      Au, Yeung Billy; Lin, Youbo; Kim, Hoon; Li, Zhengwen; Gordon, Roy Gerald (2011)
    • Atomic Layer Deposition of \(Sc_2O_3\) for Passivating AlGaN/GaN High Electron Mobility Transistor Devices 

      Wang, Xinwei; Saadat, Omair I.; Xi, Bin; Lou, Xiabing; Molnar, Richard J.; Palacios, Tomás; Gordon, Roy Gerald (American Institute of Physics, 2012)
      Polycrystalline, partially epitaxial \(Sc_2O_3\) films were grown on AlGaN/GaN substrates by atomic layer deposition (ALD). With this ALD \(Sc_2O_3\) film as the insulator layer, the \(Sc_2O_3\)/AlGaN/GaN metal-insulator- ...
    • Atomic layer deposition of Al-incorporated Zn(O,S) thin films with tunable electrical properties 

      Park, Helen Hejin; Jayaraman, Ashwin N Kr; Heasley, Rachel Lenox; Yang, Chuanxi; Hartle, Lauren Ann; Mankad, Ravin; Haight, Richard; Mitzi, David B.; Gunawan, Oki; Gordon, Roy Gerald (AIP Publishing, 2014)
      Zinc oxysulfide, Zn(O,S), films grown by atomic layer deposition were incorporated with aluminum to adjust the carrier concentration. The electron carrier concentration increased up to one order of magnitude from 1019 to ...