Now showing items 13292-13311 of 24540

    • Mediating Information 1450-1800 

      Blair, Ann M.; Stallybrass, Peter (University of Chicago Press, 2010)
      This chapter argues that the Enlightenment involved not so much a radical break with, but an inheritance of, established technologies for storing, organizing, and retrieving information. In the long history of information ...
    • Mediating Information, 1450–1800 

      Blair, Ann M.; Stallybrass, Peter (2010)
    • Mediation: R Package for Causal Mediation Analysis 

      Tingley, Dustin; Yamamoto, Teppei; Hirose, Kentaro; Keele, Luke; Imai, Kosuke (Foundation for Open Access Statistic, 2014)
      In this paper, we describe the R package mediation for conducting causal mediation analysis in applied empirical research. In many scientific disciplines, the goal of researchers is not only estimating causal effects of a ...
    • Mediator Kinase Inhibition Further Activates Super-Enhancer Associated Genes in AML 

      Pelish, Henry E.; Liau, Brian B.; Nitulescu, Ioana I.; Tangpeerachaikul, Anupong; Poss, Zachary C.; Da Silva, Diogo H.; Caruso, Brittany T.; Arefolov, Alexander; Fadeyi, Olugbeminiyi; Christie, Amanda L.; Du, Karrie; Banka, Deepti; Schneider, Elisabeth V.; Jestel, Anja; Zou, Ge; Si, Chong; Ebmeier, Christopher C.; Bronson, Roderick T.; Krivtsov, Andrei V.; Myers, Andrew G.; Kohl, Nancy E.; Kung, Andrew L.; Armstrong, Scott A.; Lemieux, Madeleine E.; Taatjes, Dylan J.; Shair, Matthew D. (2015)
      Super-enhancers (SEs), which are composed of large clusters of enhancers densely loaded with the Mediator complex, transcription factors (TFs), and chromatin regulators, drive high expression of genes implicated in cell ...
    • Mediator Subunit Med28 Is Essential for Mouse Peri-Implantation Development and Pluripotency 

      Li, Lin; Walsh, Ryan M.; Wagh, Vilas; James, Marianne F.; Beauchamp, Roberta L.; Chang, Yuh-Shin; Gusella, James F.; Hochedlinger, Konrad; Ramesh, Vijaya (Public Library of Science, 2015)
      The multi-subunit mammalian Mediator complex acts as an integrator of transcriptional regulation by RNA Polymerase II, and has emerged as a master coordinator of development and cell fate determination. We previously ...
    • Medical education in the United States: do residents feel prepared? 

      Chen, Chen (Amy); Kotliar, Dylan; Drolet, Brian C. (Bohn Stafleu van Loghum, 2015)
      Background: Medical schools face a growing challenge in providing a comprehensive educational experience. Students must graduate with not only the medical knowledge but also the requisite skills to care for patients and ...
    • Medical Nemesis? 

      Brandt, Allan M. (Johns Hopkins University Press, 1985)
    • Medical Regret without Remorse: A Moral History of Harm, Responsibility, and Emotion in American Surgery since 1945 

      Moses, Jacob David (2020-09-10)
      This dissertation chronicles moments of reconsideration regarding what constitutes medical harm through the lens of “medical regret.” It mobilizes medical history to interrogate questions of ethics, policy, and clinical ...
    • Medical Research on Animals and the Question of Moral Standing 

      Korsgaard, Christine (Harvard Medical School, 2020)
      This paper examines the difference between utilitarian and Kantian accounts of what it means to have moral standing and why non-human animals have it. It then considers the implications of these views for the question ...
    • Medical Spending Differences in the United States and Canada: The Role of Prices, Procedures, and Administrative Expenses 

      Pozen, Alexis; Cutler, David M. (Taylor & Francis, 2010)
      The United States far outspends Canada on health care, but the sources of additional spending are unclear. We evaluated the importance of incomes, administration, and medical interventions in this difference. Pooling various ...
    • Medication Adherence and Healthcare Disparities: Impact of Statin Co-Payment Reduction 

      Lewey, Jennifer; Shrank, William; Avorn, Jerry Lewis; Liu, Jun; Choudhry, Niteesh Kumar (Managed Care & Healthcare Communications, 2015)
      Objectives: Minority patients have lower rates of cardiovascularmedication adherence, which may be amenable to co-payment reductions.Our objective was to evaluate the effect of race on adherencechanges following a statin ...
    • Medicine and Community in Victorian Britain 

      Rosenberg, Charles (Massachusetts Institute of Technology Press, 1981)
    • Medicine and Cosmology in Classical Greece: First Principles in Early Greek Medicine 

      Camden, David Hayden (2016-09-06)
      In the fifth and fourth centuries BCE, a number of “doctor-cosmologists” attempted to base the art of healing on the elements, laws, and fundamental forces that govern the universe as a whole. This study examines the major ...
    • Medicine as Storytelling: Emplotment Strategies in the Definition of Illness and Healing (1870-1930) 

      Fratto, Elena (2016-04-11)
      This dissertation analyzes medical and literary sources from Russia, Italy, and France in the years 1870-1930. By tracking imagery, rhetorical devices and, above all, emplotment strategies that are employed in medical texts ...
    • Medicines, Markets, and the State 

      Barber, Melissa (2023-05-12)
      This dissertation investigates the dynamics of different market failures in global pharmaceutical markets. It explores how pharmaceutical markets are shaped by state intervention or the absence of state intervention. ...
    • Medieval Hypertext: The Illuminated Manuscript in an Age of Virtual Reproduction 

      Hamburger, Jeffrey F.; Marti, Susan; Massey, Drew (Böhlau Köln, 2011)
    • Medieval Irish Chronicles Reveal Persistent Volcanic Forcing of Severe Winter Cold Events, 431–1649 CE 

      Ludlow, Francis Michael; Stine, Alexander Robin; Leahy, Paul; Murphy, Enda; Mayewski, Paul A.; Taylor, David; Killen, James; Baillie, Michael G. L.; Hennessy, Mark; Kiely, Gerard (IOP Publishing, 2013)
      Explosive volcanism resulting in stratospheric injection of sulfate aerosol is a major driver of regional to global climatic variability on interannual and longer timescales. However, much of our knowledge of the climatic ...
    • The Mediterranean in the English Empire of Trade, 1660-1748 

      Stein, Tristan (2013-02-11)
      This dissertation reintegrates the Mediterranean into the history of the development of the early modern British Empire. During the seventeenth century, the Mediterranean emerged as a distinct political, legal and commercial ...
    • The Mediterranean Outflow as an Example of a Deep Buoyancy-Driven Flow 

      Tziperman, Eli (American Geophysical Union, 1987)
      Motivated by the Mediterranean outflow into the North Atlantic, a simple diffusive layer model of a deep buoyancy-driven circulation driven by a middepth inflow from the eastern boundary is developed. Cross-interfacial ...
    • Medium at the Margins: Bruce Nauman at the End of the Sixties 

      Walsh, Taylor (2021-05-17)
      For the American artist Bruce Nauman (b. 1941), medium is a problem. Nauman graduated from art school in 1966, entering the profession at a moment of seismic change. The very notion of a specific medium—an artwork’s material ...