Browsing Faculty of Arts and Sciences by Title
Now showing items 1927-1946 of 24540
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Biophysics of Kinetochore-Microtubule Interaction: Quantitative Measurement of NDC80 Binding in Cell Using FLIM-FRET
(2017-05-12)Chromosome motion during cell division is driven by coupling the dynamic ends of microtubules to the kinetochore. Erroneous kinetochore-microtubule attachments frequently occur in early mitosis, but are corrected to prevent ... -
Biophysics of Molecular Gastronomy
(Elsevier BV, 2015-03)Chefs and scientists exploring biophysical processes have given rise to molecular gastronomy. In this Commentary, we describe how a scientific understanding of recipes and techniques facilitates the development of new ... -
The Biophysics of Vertebrate Hearing: A Single-Molecule Approach
(2015-05-22)Inner-ear mechanotransduction relies on tip links, fine protein filaments made of cadherin-23 and protocadherin-15 that convey tension to mechanosensitive channels at the tips of hair-cell stereocilia. The tip-link cadherins ... -
Biopolymer network geometries: Characterization, regeneration, and elastic properties
(American Physical Society, 2010)We study the geometry of biopolymer networks and effects of the geometry on bulk mechanical properties. It is shown numerically that the physical network geometry can be quantified statistically and regenerated from its ... -
Biopolymer Structure Simulation and Optimization via Fragment Regrowth Monte Carlo
(American Institute of Physics, 2007)An efficient exploration of the configuration space of a biopolymer is essential for its structure modeling and prediction. In this study, the authors propose a new Monte Carlo method, fragment regrowth via energy-guided ... -
Bioprinting of 3D Convoluted Renal Proximal Tubules on Perfusable Chips
(Nature Publishing Group, 2016)Three-dimensional models of kidney tissue that recapitulate human responses are needed for drug screening, disease modeling, and, ultimately, kidney organ engineering. Here, we report a bioprinting method for creating 3D ... -
The biopsychosocial model of stress in adolescence: self-awareness of performance versus stress reactivity
(Informa UK Limited, 2014)Extensive research among adults supports the biopsychosocial (BPS) model of challenge and threat, which describes relationships among stress appraisals, physiological stress reactivity, and performance; however, no previous ... -
Bioresponsive matrices in drug delivery
(Springer Science + Business Media, 2010)For years, the field of drug delivery has focused on (1) controlling the release of a therapeutic and (2) targeting the therapeutic to a specific cell type. These research endeavors have concentrated mainly on the development ... -
A biorobotic model of the suction-feeding system in largemouth bass: the roles of motor program speed and hyoid kinematics
(The Company of Biologists, 2016)The vast majority of ray-finned fishes capture prey through suction feeding. The basis of this behavior is the generation of subambient pressure through rapid expansion of a highly kinetic skull. Over the last four decades, ... -
Biosensing for Multiplexed Genome Engineering: Applications in Renewable Chemical Production
(2015-05-15)Engineered biological systems are increasingly used to produce fuels, pharmaceuticals and industrial chemicals. While transforming cells into renewable chemical factories presents an enormous opportunity, development ... -
Biosensor Platforms for Molecular Analyses of Circulating Cancer Biomarkers
(2013-10-15)Solid cancers often shed (sub)cellular materials into the circulation, such as circulating tumor cells and extracellular microvesicles. Mounting evidence supports that these circulating materials could serve as surrogate ... -
Biosocial Approaches to the 2013-2016 Ebola Pandemic
(Harvard University Press, 2016)Abstract Despite more than 25 documented outbreaks of Ebola since 1976, our understanding of the disease is limited, in particular the social, political, ecological, and economic forces that promote (or limit) its spread. ... -
Biostratigraphic and Chemostratigraphic Correlation of Neoproterozoic Sedimentary Successions: Upper Tindir Group, Northwestern Canada, as a Test Case
(Geological Society of America, 1992)Recent advances in Proterozoic micropaleontology and sedimentary isotope geochemistry suggest that improved interbasinal correlation of Neoproterozoic (1000-540 Ma) successions is possible. Because widely varying interpretations ... -
The biosynthesis of cyanobacterial sunscreen scytonemin in intertidal microbial mat communities
(Wiley-Blackwell, 2011)We have examined the biosynthesis and accumulation of cyanobacterial sunscreening pigment scytonemin within intertidal microbial mat communities using a combination of chemical, molecular, and phylogenetic approaches. Both ... -
The Biotic Crisis and the Future of Evolution
(National Academy of Sciences, 2001)The biotic crisis overtaking our planet is likely to precipitate a major extinction of species. That much is well known. Not so well known but probably more significant in the long term is that the crisis will surely disrupt ... -
Bipolar Diffusion of Current Carriers in the Presence of Deep Traps
(1957)We have investigated bipolar diffusion in the presence of traps, taking into consideration the dependence of minority carrier lifetime on the population of the traps, and have established criteria for the validity of the ... -
A Bird's Eye View of Neural Circuit Formation
(Elsevier, 2011)Neural circuits underlying complex learned behaviors, such as speech in humans, develop under genetic constraints and in response to environmental influences. Little is known about the rules and mechanisms through which ... -
Birdie or Bogey? How Golf Course Construction Affects Surrounding Home Values
(2023-06-30)When asked to think about the how building a golf course can affect a commu- nity, many people’s first thought may jump to the environmental impacts that such construction has on the surrounding area. However, the economic ... -
Birds have paedomorphic dinosaur skulls
(Nature Publishing Group, 2012)The interplay of evolution and development has been at the heart of evolutionary theory for more than a century. Heterochrony—change in the timing or rate of developmental events—has been implicated in the evolution of ... -
Birds of a Feather: Patterns, Heuristics, and Constraints of Cross-Boundary Marriage Sorting
(2017-05-13)I examine of the patterns, heuristics, and constraints of contemporary marriage sorting across various social boundaries and the resulting implications for understanding social openness and closure. Using a combination of ...