Browsing Faculty of Arts and Sciences by Title

Now showing items 2505-2524 of 24540

    • Cell-Cycle Dependent Expression of a Translocation-Mediated Fusion Oncogene Mediates Checkpoint Adaptation in Rhabdomyosarcoma 

      Kikuchi, Ken; Hettmer, Simone; Aslam, M. Imran; Michalek, Joel E.; Laub, Wolfram; Wilky, Breelyn A.; Loeb, David M.; Rubin, Brian P.; Wagers, Amy J.; Keller, Charles (Public Library of Science, 2014)
      Rhabdomyosarcoma is the most commonly occurring soft-tissue sarcoma in childhood. Most rhabdomyosarcoma falls into one of two biologically distinct subgroups represented by alveolar or embryonal histology. The alveolar ...

    • Cell-to-cell coupling in engineered pairs of rat ventricular cardiomyocytes: relation between Cx43 immunofluorescence and intercellular electrical conductance 

      McCain, Megan; Desplantez, Thomas; Geisse, Nicholas A.; Rothen-Rutishauser, Barbara; Oberer, Helene; Parker, Kevin Kit; Kleber, Andre (American Physiological Society, 2012)
      Gap junctions are composed of connexin (Cx) proteins, which mediate intercellular communication. Cx43 is the dominant Cx in ventricular myocardium, and Cx45 is present in trace amounts. Cx43 immunosignal has been associated ...

    • Cellular and Biochemical Events in Toll-like Receptor Signaling 

      Bonham, Kevin Scott (2014-06-06)
      In multicellular organisms, communication between cells relies on transmitting information across membrane barriers. Different cell types interrogate particular aspects of their surrounding environment through protein ...

    • Cellular and Genetic Dynamics of the Melanoma Microenvironment 

      Stirtz, Georgia Layne (2023-04-26)
      The tumor microenvironment is comprised of a diverse assemblage of cells. These populations dynamically interact with one another in varied ways that modify the individual cells and shape the overall trajectory of the ...

    • Cellular and Molecular Mechanisms of Chronic Inflammation in Aging of Skeletal Muscle 

      Oh, Juhyun (2015-05-13)
      Aging of skeletal muscle is typically accompanied by declining regenerative potential, due in part to alternations in the resident muscle stem cell population, known as satellite cells. Previous data suggest that highly ...

    • Cellular and synaptic mechanisms controlling cerebellar output 

      Khan, Mehak Majid (2021-05-13)
      The deep cerebellar nuclei (DCN) provide the major output of the cerebellum, projecting to premotor nuclei as well as non-motor areas in the brain. The dominant input to the DCN is provided by the output cells of cerebellar ...

    • Cellular and Systemic Metabolic Adaptations to Energy Status 

      Calay, Ediz Suha (2014-06-06)
      My thesis work has focused on physiological adaptations to nutrient stress; from genes, environment and hormonal perspective, and how failure of these systems result in common chronic diseases.

    • Cellular cooperation with shift updating and repulsion 

      Pavlogiannis, Andreas; Chatterjee, Krishnendu; Adlam, Ben; Nowak, Martin A. (Nature Publishing Group, 2015)
      Population structure can facilitate evolution of cooperation. In a structured population, cooperators can form clusters which resist exploitation by defectors. Recently, it was observed that a shift update rule is an ...

    • Cellular Hydraulics Suggests a Poroelastic Cytoplasm Rheology 

      Moeendarbary, E.; Valon, L.; Fritzsche, M.; Harris, A. R.; Moulding, D. A.; Thrasher, A. J.; Stride, E.; Mahadevan, Lakshminarayanan; Charras, G. T. (Nature Publishing Group, 2013-01-07)
      The cytoplasm represents the largest part of the cell by volume and hence its rheology sets the rate at which cellular shape change can occur. Recent experimental evidence suggests that cytoplasmic rheology can be described ...

    • Cellular Interrogation: Exploiting Cell-to-Cell Variability to Discriminate Regulatory Mechanisms in Oscillatory Signalling 

      Estrada, Javier; Andrew, Natalie; Gibson, Daniel; Chang, Frederick; Gnad, Florian; Gunawardena, Jeremy (Public Library of Science, 2016)
      The molecular complexity within a cell may be seen as an evolutionary response to the external complexity of the cell’s environment. This suggests that the external environment may be harnessed to interrogate the cell’s ...

    • Cellular Metabolism Modulates Ion Channels That Regulate Neuronal Excitability 

      Lutas, Andrew (2015-05-01)
      Epilepsy is a common neurological disorder, affecting around 1% of the world’s population. For many, drugs are available that can prevent their seizures. However, for close to one third of those who suffer from epilepsy, ...

    • Cellular nanoscale stiffness patterns governed by intracellular forces 

      Friedsam, Claudia; Sahin, Ozgur; Mandriota, Nicola; Jones-Molina, John; Tatem, Kathleen; Ingber, Donald (Springer Science and Business Media LLC, 2019-06-17)
      Cell stiffness measurements have led to insights into various physiological and pathological processes. Although many cellular behaviours are influenced by intracellular mechanical forces that also alter the material ...

    • Cellular Resolution Imaging in a Rodent Model for High-Level Vision 

      Rhee, Juliana Yoo-Min (2021-07-12)
      Vision is critical for guiding behavior in species throughout the animal kingdom. Nonhuman primates have long been classic models for vision, but over the last decade, rodents have emerged as highly promising alternatives. ...

    • Cellular Targets of Propranolol in Infantile Hemangioma 

      Lee, Daniel K (2014-02-25)
      Infantile hemangioma (IH) is a vascular neoplasm that affects 4-10 percent of infants. Propranolol, a non-selective beta-adrenergic receptor (AR) antagonist, was serendipitously discovered to accelerate regression of IH ...

    • Cellular uptake mechanisms and endosomal trafficking of supercharged proteins 

      Thompson, David B.; Villaseñor, Roberto; Dorr, B; Zerial, Marino; Liu, David Ruchien (Elsevier BV, 2012)
      Supercharged proteins can deliver functional macromolecules into the cytoplasm of mammalian cells with potencies that exceed those of cationic peptides. The structural features of supercharged proteins that determine their ...

    • The Celtic Nations and the African Americas 

      Sollors, Werner (Informa UK Limited, 2010)

    • cem: Coarsened Exact Matching in Stata 

      Blackwell, Matthew; Iacus, Stefano; King, Gary; Porro, Giuseppe (StataCorp, 2010)
      This paper introduces a Stata implementation of Coarsened Exact Matching (CEM), a new method for improving the estimation of causal effects by reducing imbalance in co-variates between treated and control groups. CEM is ...

    • CEM: Software for Coarsened Exact Matching 

      Iacus, Stefano; King, Gary; Porro, Giuseppe (American Statistical Association, 2009)
      This program is designed to improve causal inference via a method of matching that is widely applicable in observational data and easy to understand and use (if you understand how to draw a histogram, you will understand ...

    • Cementing mussels to oysters in the pteriomorphian tree: a phylogenomic approach 

      Lemer, Sarah; González, Vanessa L.; Bieler, Rüdiger; Giribet, Gonzalo (The Royal Society, 2016)
      Mussels (Mytilida) are a group of bivalves with ancient origins and some of the most important commercial shellfish worldwide. Mytilida consists of approximately 400 species found in various littoral and deep-sea environments, ...

    • CEMP stars: possible hosts to carbon planets in the early Universe 

      Mashian, Natalie; Loeb, Abraham (Oxford University Press (OUP), 2016)
      We explore the possibility of planet formation in the carbon-rich protoplanetary disks of carbon-enhanced metal-poor (CEMP) stars, possible relics of the early Universe. The chemically anomalous abundance patterns ([C/Fe] ...