Browsing Faculty of Arts and Sciences by Title
Now showing items 716-735 of 24540
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All-Optical Neurophysiology in the 1-Photon Regime
(2018-05-13)Simultaneous optical recording and optical stimulation of neuronal activity could enable faster and more comprehensive investigation of neuronal function but is hampered by underdeveloped tools. Pairs of molecular transducers ... -
All-Optical Sensing of a Single-Molecule Electron Spin
(American Chemical Society (ACS), 2014)We demonstrate an all-optical method for magnetic sensing of individual molecules in ambient conditions at room temperature. Our approach is based on shallow nitrogen-vacancy (NV) centers near the surface of a diamond ... -
All-Optical Switch and Transistor Gated by One Stored Photon
(American Association for the Advancement of Science (AAAS), 2013)The realization of an all-optical transistor, in which one “gate” photon controls a “source” light beam, is a long-standing goal in optics. By stopping a light pulse in an atomic ensemble contained inside an optical ... -
All-Time Releases of Mercury to the Atmosphere from Human Activities
(American Chemical Society (ACS), 2011)Understanding the biogeochemical cycling of mercury is critical for explaining the presence of mercury in remote regions of the world, such as the Arctic and the Himalayas, as well as local concentrations. While we have ... -
All-Weather Calibration of Wide-Field Optical and NIR Surveys
(IOP Publishing, 2013)The science goals for ground-based large-area surveys, such as the Dark Energy Survey, Pan-STARRS, and the Large Synoptic Survey Telescope, require calibration of broadband photometry that is stable in time and uniform ... -
Allele-specific detection of single mRNA molecules in situ
(2013)We describe a method for fluorescent in situ identification of individual mRNA molecules, allowing quantitative and accurate measurements of allele-specific transcripts that differ by only a few nucleotides, in single ... -
Allele-specific detection of single mRNA molecules in situ and the study of transcriptional regulation
(2014-10-21)We developed a method for fluorescence in situ identification of individual mRNA molecules, allowing quantitative and accurate measurement, in single cells, of allele-specific transcripts that differ by only a few nucleotides. ... -
Allele-Specific Gene Expression in the Laboratory Mouse
(2013-02-07)Traditionally, autosomal genes, when expressed, are assumed to express both alleles equally. Exceptions to this tenet include genes for which a specific genotypic polymorphism controls expression level, as well as genes ... -
Allelic imbalance of chromatin accessibility in cancer identifies candidate causal risk variants and their mechanisms
(2022-09-07)Understanding the functional impact of non-coding variants remains a major challenge in cancer genetics. In the case of non-coding germline risk associations from GWAS, many associations are in high LD and cannot be resolved ... -
Allene Synthesis from 2-Alkyn-1-Ols
(Elsevier, 1989)Activation of 2-alkyn-1-01s as their methanesulfonate esters and displacement with hydrazine urnishes the corresponding alkynyl hydrazine derivatives which undergo smooth oxidative rearrangement with diethyl azodicarboxylate ... -
Allocating Payroll Tax Revenue to Personal Retirement Accounts to Maintain Social Security Benefits and the Payroll Tax Rate
(National Bureau of Economic Research, 2000)In an earlier paper we analyzed a method of combining traditional tax financed pay-as-you-go Social Security benefits with annuities financed by Personal Retirement Accounts. We showed that such a combination could maintain ... -
The Allocation of Talent: Implications for Growth
(Oxford University Press (OUP), 1991)A country's most talented people typically organize production by others, so they can spread their ability advantage over a larger scale. When they start firms, they innovate and foster growth, but when they become rent ... -
The Allocation of Time in Decision-Making
(Massachusetts Institute of Technology Press, 2009)We study the allocation of time across decision problems. If a decision-maker (1) has noisy estimates of value, (2) improves those estimates the longer he or she analyzes a choice problem, and (3) allocates time optimally, ... -
Allometric rules for mammalian cortical layer 5 neuron biophysics
(Springer Science and Business Media LLC, 2021-11-10) -
Allosteric Communication in Myosin V: From Small Conformational Changes to Large Directed Movements
(Public Library of Science, 2008)The rigor to post-rigor transition in myosin, a consequence of ATP binding, plays an essential role in the Lymn–Taylor functional cycle because it results in the dissociation of the actomyosin complex after the powerstroke. ... -
Allosteric Integrase Inhibitors Reveal a Role for Integrase During HIV-1 Maturation
(2015-09-20)Integration of the DNA copy of the HIV-1 genome is an essential step for virus replication and is mediated by a homotetrameric complex of the viral protein integrase (IN) in association with the ends of linear viral DNA ... -
Allowing Spontaneity: Practice, Theory, and Ethical Cultivation in Longchenpa's Great Perfection Philosophy of Action
(2018-05-11)This is a study of the philosophy of practical action in the Great Perfection poetry and spiritual exercises of the fourteenth century Tibetan author, Longchen Rabjampa Drime Ozer (klong chen rab 'byams pa dri med 'od zer ... -
ALLPATHS 2: Small Genomes Assembled Accurately and with High Continuity from Short Paired Reads
(BioMed Central, 2009)We demonstrate that genome sequences approaching finished quality can be generated from short paired reads. Using 36 base (fragment) and 26 base (jumping) reads from five microbial genomes of varied GC composition and sizes ... -
Alma Imaging of Hcn, Cs, and Dust in Arp 220 and Ngc 6240
(American Astronomical Society, 2015)We report ALMA Band 7 (350 GHz) imaging at 0".4-0".6 resolution and Band 9 (696 GHz) at similar to 0".25 resolution of the luminous IR galaxies Arp 220 and NGC 6240. The long wavelength dust continuum is used to estimate ... -
ALMA Observations of the Host Galaxy of GRB 090423 at Z = 8.23: Deep Limits on Obscured Star formation 630 Million Years after the Big Bang.
(IOP Publishing, 2014)We present rest-frame far-infrared (FIR) and optical observations of the host galaxy of GRB 090423 at z = 8.23 from the Atacama Large Millimeter Array (ALMA) and the Spitzer Space Telescope, respectively. The host remains ...