Browsing Faculty of Arts and Sciences by Title

Now showing items 7696-7715 of 24540

    • An exploratory randomised double-blind and placebo-controlled phase 2 study of a combination of baclofen, naltrexone and sorbitol (PXT3003) in patients with Charcot-Marie-Tooth disease type 1A 

      Attarian, Shahram; Vallat, Jean-Michel; Magy, Laurent; Funalot, Benoît; Gonnaud, Pierre-Marie; Lacour, Arnaud; Péréon, Yann; Dubourg, Odile; Pouget, Jean; Micallef, Joëlle; Franques, Jérôme; Lefebvre, Marie-Noëlle; Ghorab, Karima; Al-Moussawi, Mahmoud; Tiffreau, Vincent; Preudhomme, Marguerite; Magot, Armelle; Leclair-Visonneau, Laurène; Stojkovic, Tanya; Bossi, Laura; Lehert, Philippe; Gilbert, Walter; Bertrand, Viviane; Mandel, Jonas; Milet, Aude; Hajj, Rodolphe; Boudiaf, Lamia; Scart-Grès, Catherine; Nabirotchkin, Serguei; Guedj, Mickael; Chumakov, Ilya; Cohen, Daniel (BioMed Central, 2014)
      Background: Charcot-Marie-Tooth type 1A disease (CMT1A) is a rare orphan inherited neuropathy caused by an autosomal dominant duplication of a gene encoding for the structural myelin protein PMP22, which induces abnormal ...

    • Exploring and Enforcing Application Security Guarantees via Program Dependence Graphs 

      Johnson, Andrew; Waye, Lucas Reed; Moore, Scott; Chong, Stephen N (2014)
      We present Pidgin, a program analysis and understanding tool that allows developers to explore the information flows that exist in programs and specify and enforce security policies that restrict these information flows. ...

    • Exploring and Enforcing Application Security Guarantees vis Program Dependence 

      Johnson, Andrew; Waye, Lucas Reed; Moore, Scott David; Chong, Stephen N (2014)
      We present Pidgin, a program analysis and understanding tool that allows developers to explore the information flows that exist in programs and specify and enforce security policies that restrict these information flows. ...

    • Exploring and enforcing security guarantees via program dependence graphs 

      Johnson, Andrew Arthur; Wayne, Lucas; Moore, Scott David; Chong, Stephen N (ACM Press, 2015)
      We present PIDGIN, a program analysis and understanding tool that enables the specification and enforcement of precise application-specific information security guarantees. PIDGIN also allows developers to interactively ...

    • Exploring Biomolecular Interactions Through Single-Molecule Force Spectroscopy and Computational Simulation 

      Yang, Darren (2016-04-11)
      Molecular interactions between cellular components such as proteins and nucleic acids govern the fundamental processes of living systems. Technological advancements in the past decade have allowed the characterization of ...

    • Exploring Black Hole Dynamics 

      Chung, Hyeyoun (2014-11-20)
      This thesis explores the evolution of different types of black holes, and the ways in which black hole dynamics can be used to answer questions about other physical systems. We first investigate the differences in ...

    • Exploring Bystander Selection for Antibiotic Resistance 

      Tedijanto, Christine (2021-03-05)
      Antibiotic consumption exerts selection for antibiotic resistance. Due to the wide spectrum of activity of many antibiotics, a single antibiotic use may impose selective pressures on a range of bacterial species, including ...

    • Exploring Cancer's Fractured Genomic Landscape: Searching for Cancer Drivers and Vulnerabilities in Somatic Copy Number Alterations 

      Zack, Travis Ian (2014-10-21)
      Somatic copy number alterations (SCNAs) are a class of alterations that lead to deviations from diploidy in developing and established tumors. A feature that distinguishes SCNAs from other alterations is their genomic ...

    • Exploring Correlations of High Altitude Aerosol Formation in Planetary Systems with Similar Parameters 

      McGruder, Chima (2023-05-11)
      High altitude aerosols prevent our ability to probe exoplanet atmospheres, by muting or completely obscuring molecular and atomic features. Unfortunately, the vast majority of planets are obscured by high altitude aerosols, ...

    • Exploring cosmic origins with CORE: Cosmological parameters 

      Valentino, E. Di; Brinckmann, T.; Gerbino, M.; Poulin, V.; Bouchet, F.R.; Lesgourgues, J.; Melchiorri, A.; Chluba, J.; Clesse, S.; Delabrouille, J.; Dvorkin, Cora; Forastieri, F.; Galli, S.; Hooper, D.C.; Lattanzi, M.; Martins, C.J.A.P.; Salvati, L.; Cabass, G.; Caputo, A.; Giusarma, E.; Hivon, E.; Natoli, P.; Pagano, L.; Paradiso, S.; Rubiño-Martin, J.A.; Achúcarro, A.; Ade, P.; Allison, R.; Arroja, F.; Ashdown, M.; Ballardini, M.; Banday, A.J.; Banerji, R.; Bartolo, N.; Bartlett, J.G.; Basak, S.; Baumann, D.; de Bernardis, P.; Bersanelli, M.; Bonaldi, A.; Bonato, M.; Borrill, J.; Boulanger, F.; Bucher, M.; Burigana, C.; Buzzelli, A.; Cai, Z.-Y.; Calvo, M.; Carvalho, C.S.; Castellano, G.; Challinor, A.; Charles, I.; Colantoni, I.; Coppolecchia, A.; Crook, M.; D'Alessandro, G.; Petris, M. De; Zotti, G. De; Diego, J.M.; Errard, J.; Feeney, S.; Fernandez-Cobos, R.; Ferraro, S.; Finelli, F.; de Gasperis, G.; Génova-Santos, R.T.; González-Nuevo, J.; Grandis, S.; Greenslade, J.; Hagstotz, S.; Hanany, S.; Handley, W.; Hazra, D.K.; Hernández-Monteagudo, C.; Hervias-Caimapo, C.; Hills, M.; Kiiveri, K.; Kisner, T.; Kitching, T.; Kunz, M.; Kurki-Suonio, H.; Lamagna, L.; Lasenby, A.; Lewis, A.; Liguori, M.; Lindholm, V.; Lopez-Caniego, M.; Luzzi, G.; Maffei, B.; Martin, S.; Martinez-Gonzalez, E.; Masi, S.; Matarrese, S.; McCarthy, D.; Melin, J.-B.; Mohr, J.J.; Molinari, D.; Monfardini, A.; Negrello, M.; Notari, A.; Paiella, A.; Paoletti, D.; Patanchon, G.; Piacentini, F.; Piat, M.; Pisano, G.; Polastri, L.; Polenta, G.; Pollo, A.; Quartin, M.; Remazeilles, M.; Roman, M.; Ringeval, C.; Tartari, A.; Tomasi, M.; Tramonte, D.; Trappe, N.; Trombetti, T.; Tucker, C.; Väliviita, J.; de Weygaert, R. van; Tent, B. Van; Vennin, V.; Vermeulen, G.; Vielva, P.; Vittorio, N.; Young, K.; Zannoni, M. (IOP Publishing, 2018-04-05)
      We forecast the main cosmological parameter constraints achievable with the CORE space mission which is dedicated to mapping the polarisation of the Cosmic Microwave Background (CMB). CORE was recently submitted in response ...

    • Exploring Defocus Matting: Nonparametric Acceleration, Super-Resolution, and Off-Center Matting 

      Joshi, Neel; Matusik, Wojciech; Avidan, Shai; Pfister, Hanspeter; Freeman, William T. (Institute of Electrical and Electronics Engineers, 2007)
      Defocus matting is a fully automatic and passive method for pulling mattes from video captured with coaxial cameras that have different depths of field and planes of focus. Nonparametric sampling can accelerate the ...

    • Exploring degrees of entanglement 

      Myers, John M.; Wu, Tai Tsun (Springer Science + Business Media, 2009)
      In spite of a long history, the quantification of entanglement still calls for exploration. What matters about entanglement depends on the situation, and so presumably do the numbers suitable for its quantification. ...

    • Exploring Dengue Virus Entry through Small Molecule Inhibition and Mutagenesis of the Envelope Protein 

      Clark, Margaret Jean (2013-03-15)
      Over one-third of the world’s population is at risk for infection with dengue virus (DENV), a mosquito-borne virus that can cause a severe febrile disease. There are no specific treatments available for dengue infection, ...

    • Exploring Dna Translocation Through a Nanopore Via a Multiscale Lattice-boltzmann Molecular-dynamics Methodology 

      Melchionna, Simone; Fyta, Maria G.; Kaxiras, Efthimios; Succi, Sauro (World Scientific Publishing, 2007)
      A multiscale approach is used to simulate the translocation of DNA through a nanopore. Within this scheme, the interactions of the molecule with the surrounding fluid (solvent) are explicitly taken into account. By generating ...

    • Exploring dynamical phase transitions and prethermalization with quantum noise of excitations 

      Smacchia, Pietro; Knap, Michael; Demler, Eugene; Silva, Alessandro (American Physical Society, 2015)
      Dynamical phase transitions can occur in isolated quantum systems that are brought out of equilibrium by sudden parameter changes. We discuss the characterization of such dynamical phase transitions based on the statistics ...

    • Exploring exact dualities in lattice models of topological phases of matter 

      Tantivasadakarn, Nathanan (2022-05-12)
      Dualities are central to our understanding of physics, in particular in the study of quantum phases of matter. In this dissertation, we explore exact lattice dualities that relate various topological phases of matter, which ...

    • Exploring Implicit Voice Theories at Work 

      Glassenberg, Aaron (2013-02-20)
      In modern organizations, individuals frequently choose silence over voice (e.g., Milliken, Morrison, & Hewlin, 2003), which can have a variety of detrimental effects on individuals and organizations. This choice of silence ...

    • Exploring Intra-tumor Cooperation in Metastasis and Drug Resistance using Heterogeneous Xenograft Models of Breast Cancer 

      Tabassum, Doris Priscilla (2016-05-03)
      Breast cancer is a highly heterogeneous disease, having not only several intrinsic sub-types but also significant sub-clonal heterogeneity within tumors. Intra-tumor heterogeneity can have profound impact on tumor evolution, ...

    • Exploring Mobile Screen Media Use Among Preschoolers and the Implications for Supporting Children’s Early Language and Literacy Skills 

      Turco, Rosa Guzman (2022-01-18)
      Technology has become an integral part of everyday life. Mobile media devices, in particular, are now an essential component of mainstream lifestyle, whereby adults rely on mobile devices not only to communicate, but also ...

    • Exploring Models for Implementing Differential Privacy 

      Balcer, Victor (2022-09-08)
      Researchers across many fields use statistical analysis on collected data to make decisions and inform policy. However, datasets collected from individuals may contain sensitive information. Ideally, we want to perform ...