Browsing Faculty of Arts and Sciences by Title
Now showing items 16756-16775 of 24540
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Polybrominated Diphenyl Ethers in Early Pregnancy and Racial/Ethnic Disparities in Pregnancy Outcomes: Findings from the NICHD Fetal Growth Studies-Singleton Cohort
(2022-11-23)Women in the U.S. are ubiquitously exposed to a class of persistent organic pollutants known as polybrominated diphenyl ethers (PBDEs), which were used as flame retardants in a variety of consumer products. Although previous ... -
A Polycomb complex remains bound through DNA replication in the absence of other eukaryotic proteins
(Nature Publishing Group, 2012)Propagation of chromatin states through DNA replication is central to epigenetic regulation and can involve recruitment of chromatin proteins to replicating chromatin through interactions with replication fork components. ... -
Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development
(Public Library of Science, 2016)An increasing amount of evidence indicates that developmental programs are tightly regulated by the complex interplay between signaling pathways, as well as transcriptional and epigenetic processes. Here, we have uncovered ... -
Polycystin-1 and Bone Mechanotransduction
(2013-02-19)Bone mechanotransduction is a fundamental process underlying the remarkable ability of bones to perceive surrounding physical cues and adapt their mass, structure and overall strength to their mechanical environment. ... -
Polygenic architecture of human body size and proportion
(2023-11-21)Over the last 15 years, genome-wide association studies (GWAS) have discovered thousands of genetic associations with human phenotypes. However, as most of these associations lie in non-coding regions and are typically ... -
Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia
(2013)Bipolar disorder and schizophrenia are two often severe disorders with high heritabilities. Recent studies have demonstrated a large overlap of genetic risk loci between these disorders but diagnostic and molecular ... -
Polyhedral Geometry and the Two-plane Parameterization
(Springer, 1997)Recently the light-field and lumigraph systems have been proposed as general methods of representing the visual information present in a scene. These methods represent this information as a 4D function of light over the ... -
Polymer Amide as an Early Topology
(Public Library of Science, 2014)Hydrophobic polymer amide (HPA) could have been one of the first normal density materials to accrete in space. We present ab initio calculations of the energetics of amino acid polymerization via gas phase collisions. The ... -
Polymer Micropatches as Cell Engagers for Cancer Immunotherapy
(2023-11-21)Adoptive transfer of immune cells has emerged as a potential therapeutic approach against various cancers. The effectiveness of cell-based therapies is limited by an inability to control the cell phenotype post in vivo ... -
Polymer Models of Topological Insulators
(BioMed Central, 2013) -
Polymer Models of Yeast S. cerevisiae Genome Organization
(BioMed Central, 2013) -
Polymer-based mesh as supports for multi-layered 3D cell culture and assays
(Elsevier BV, 2014)Three-dimensional (3D) culture systems can mimic certain aspects of the cellular microenvironment found in vivo, but generation, analysis and imaging of current model systems for 3D cellular constructs and tissues remain ... -
Polymerization-based Signal Amplification for Paper-Based Immunoassays
(Royal Society of Chemistry (RSC), 2015)Diagnostic tests in resource-limited settings require technologies that are affordable and easy to use with minimal infrastructure. Colorimetric detection methods that produce results that are readable by eye, without ... -
Polymorphism and Separation in Hoare Type Theory
(2006)In previous work we have proposed a Dependent Hoare Type Theory (HTT) as a framework for development and reasoning about higher-order functional programs with effects of state, aliasing and nontermination. The main feature ... -
Polymorphisms in the estrogen receptor alpha gene (ESR1), daily cycling estrogen and mammographic density phenotypes.
(BioMed Central, 2016)Background: Single nucleotide polymorphisms (SNPs) involved in the estrogen pathway and SNPs in the estrogen receptor alpha gene (ESR1 6q25) have been linked to breast cancer development, and mammographic density is an ... -
Polymorphisms in the Gene That Encodes the Iron Transport Protein Ferroportin 1 Influence Susceptibility to Tuberculosis
(Oxford University Press, 2012)Background: We studied the association between iron intake and polymorphisms in the iron transporter gene, SLC40A1, and the risk of tuberculosis. Methods: We compared iron intake, the frequency of SLC40A1 mutations, and ... -
Polynomial Algorithms for the Maximal Pairing Problem: Efficient Phylogenetic Targeting on Arbitrary Trees
(BioMed Central, 2010)Background: The Maximal Pairing Problem (MPP) is the prototype of a class of combinatorial optimization problems that are of considerable interest in bioinformatics: Given an arbitrary phylogenetic tree T and weights ωxy ... -
Polynomial Approximations for Quantum Hamiltonian Complexity
(2023-06-30)Quantum Hamiltonian Complexity (QHC) sits at the intersection of quantum complexity theory and quantum many-body physics. However, many results in QHC still remain disconnected across domains. The technique of polynomial ... -
Polynomial Invariants for Fibered 3-Manifolds and Teichmuller Geodesics for Foliations
(Elsevier, 2000)Let Image be a fibered face of the Thurston norm ball for a hyperbolic 3-manifold M. Any Image determines a measured foliation Image of M. Generalizing the case of Teichmüller geodesics and fibrations, we show Image ...