Now showing items 2988-3007 of 24465

    • Clinical Sequencing Uncovers Origins and Evolution of Lassa Virus 

      Sabeti, Pardis Christine (Elsevier BV, 2015)
      The 2013-2015 West African epidemic of Ebola virus disease (EVD) reminds us how little is known about biosafety level-4 viruses. Like Ebola virus, Lassa virus (LASV) can cause hemorrhagic fever with high case fatality ...
    • The clinical significance of snail protein expression in gastric cancer: a meta-analysis 

      Chen, Xiaoya; Li, Jinjun; Hu, Ling; Yang, William; Lu, Lili; Jin, Hongyan; Wei, Zexiong; Yang, Jack Y.; Arabnia, Hamid R.; Liu, Jun S.; Yang, Mary Qu; Deng, Youping (BioMed Central, 2016)
      Background: Snail is a typical transcription factor that could induce epithelial-mesenchymal transition (EMT) and cancer progression. There are some related reports about the clinical significance of snail protein expression ...
    • Clinical trial data science to advance precision oncology 

      Plana, Deborah (2022-04-04)
      Clinical trials are the most expensive and highest-stakes experiments in biomedicine, and their results determine which therapies are ultimately used to treat patients. While a typical pivotal trial costs millions of dollars ...
    • Clinical Validation of a Cas13-Based Assay for the Detection of SARS-CoV-2 RNA 

      Petchsung, Maturada; Jantarug, Krittapas; Pattama, Archiraya; Aphicho, Kanokpol; Suraritdechachai, Surased; Meesawat, Piyachat; Sappakhaw, Khomkrit; Leelahakorn, Nattawat; Ruenkam, Theerawat; Wongsatit, Thanakrit; Athipanyasilp, Niracha; Eiamthong, Bhumrapee; Lakkanasirorat, Benya; Phoodokmai, Thitima; Niljianskul, Nootaree; Pakotiprapha, Danaya; Chanarat, Sittinan; Homchan, Aimorn; Tinikul, Ruchanok; Kamutira, Philaiwarong; Phiwkaow, Kochakorn; Soithongcharoen, Sahachat; Kantiwiriyawanitch, Chadaporn; Pongsupasa, Vinutsada; Trisrivirat, Duangthip; Jaroensuk, Juthamas; Wongnate, Thanyaporn; Maenpuen, Somchart; Chaiyen, Pimchai; Kamnerdnakta, Sirichai; Swangsri, Jirawat; Chuthapisith, Suebwong; Sirivatanauksorn, Yongyut; Chaimayo, Chutikarn; Sutthent, Ruengpung; Kantakamalakul, Wannee; Joung, Julia; Ladha, Alim; Jin, Xin; Gootenberg, Jonathan; Abudayyeh, Omar; Zhang, Feng; Horthongkham, Navin; Uttamapinant, Chayasith; Uttamapinant (2020-08-26)
    • Clinicians’ knowledge and practices regarding family planning and intrauterine devices in China, Kazakhstan, Laos and Mexico 

      Hoffman, Steven J.; Guindon, G. Emmanuel; Lavis, John N.; Randhawa, Harkanwal; Becerra-Posada, Francisco; Boupha, Boungnong; Shi, Guang; Turdaliyeva, Botagoz S.; Cameron, David; Qiu, Tinglin; Osei, Eric J. A.; Dovlo, Kudjoe; Yesudian, C. A. K.; Ramachandran, P.; Malek-Afzali, Hossein; Dejman, M.; Falahat, K.; Baradaran, M.; Habibi, E.; Kohanzad, H.; Nasehi, M.; Salek, S.; Akanov, A. A.; Turdaliyeva, B. S.; Hamzina, N. K.; Tulebaev, K. A.; Clazhneva, T. I.; Battakova, G.; Kounnavong, Sengchanh; Siengsounthone, Latsamy; Ramos, Leticia Alfaro; Mejia, Israel; Akhtar, Tasleem; Khan, M. Mubashir A.; Sidibe, Mintou Fall; Sidibe, Awa; Ndiaye, Djiby; Ndossi, Godwin D.; Massaga, Julius; Sadana, Ritu; Pang, Tikki (BioMed Central, 2016)
      Background: It is widely agreed that the practices of clinicians should be based on the best available research evidence, but too often this evidence is not reliably disseminated to people who can make use of it. This ...
    • Clio and Caring: An Agenda for American Historians and Nursing 

      Rosenberg, Charles (American Journal of Nursing Co., 1987)
    • Cliometrics and the Nobel 

      Goldin, Claudia D. (American Economic Association, 1995)
      In October 1993, the Royal Swedish Academy of Sciences awarded the Nobel Prize in Economics to Robert William Fogel and Douglass Cecil North `for having renewed research in economic history.' The Academy noted that `they ...
    • The clitic binding restriction revisited: Evidence for antilogophoricity 

      Charnavel, Isabelle Carole; Mateu, Victoria (Walter de Gruyter GmbH, 2015)
      In some Romance languages, including French and Spanish, there is an interesting asymmetry concerning the behavior of isolated clitics and clitic clusters with respect to coreference. In the French example Anne croit qu’on ...
    • Clitic positions within the Left Periphery: evidence for a phonological buffer 

      Szczegielniak, Adam (John Benjamins, 2005)
      In this paper I will argue that Polish auxiliary clitics provide additional evidence for adopting Rizzi’s (1997) expanded structure of the Left Periphery (LP) by arguing that auxiliary clitics are a phonological manifestation ...
    • Clock quantum Monte Carlo technique: An imaginary-time method for real-time quantum dynamics 

      McClean, Jarrod Ryan; Aspuru-Guzik, Alan (American Physical Society (APS), 2015)
      In quantum information theory, there is an explicit mapping between general unitary dynamics and Hermitian ground-state eigenvalue problems known as the Feynman-Kitaev clock Hamiltonian. A prominent family of methods for ...
    • Clogging Mechanisms in Converging Microchannels 

      Massenburg, Sorell S. (2016-01-29)
      Many technological and biomedical applications ranging from water filtration and oil extraction to arteriosclerosis and vein thrombosis rely upon the transport of solids in liquids. Particulate matter suspended in liquid ...
    • Clonal analyses and gene profiling identify genetic biomarkers of human brown and white preadipocyte thermogenic potential 

      Xue, Ruidan; Lynes, Matthew D.; Dreyfuss, Jonathan M.; Shamsi, Farnaz; Schulz, Tim J.; Zhang, Hongbin; Huang, Tian Lian; Townsend, Kristy L.; Li, Yiming; Takahashi, Hirokazu; Weiner, Lauren S.; White, Andrew P.; Lynes, Maureen S.; Rubin, Lee L.; Goodyear, Laurie J.; Cypess, Aaron M.; Tseng, Yu-Hua (2015)
      Targeting brown adipose tissue (BAT) content or activity has therapeutic potential for treating obesity and the metabolic syndrome by increasing energy expenditure. Both inter- and intra-individual differences contribute ...
    • Clonal Analysis of Mucosal SIV-Specific CD8+ T Cell Responses 

      Sircar, Piya (2013-02-26)
      CD8+ T cells responses are critical in the immune defense against human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infection. A major challenge for vaccine development is that HIV/SIV can rapidly ...
    • Clonal analysis of native and malignant hematopoiesis using color barcoding in zebrafish 

      Henninger, Jonathan (2018-01-19)
      Hematopoietic stem cells (HSCs) emerge from the dorsal aorta during embryogenesis and sustain lifelong blood production. Over time, HSC clones accumulate mutations that may cause clonal expansion at the expense of normal ...
    • Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition 

      Burger, Jan A.; Landau, Dan A.; Taylor-Weiner, Amaro; Bozic, Ivana; Zhang, Huidan; Sarosiek, Kristopher; Wang, Lili; Stewart, Chip; Fan, Jean; Hoellenriegel, Julia; Sivina, Mariela; Dubuc, Adrian M.; Fraser, Cameron; Han, Yulong; Li, Shuqiang; Livak, Kenneth J.; Zou, Lihua; Wan, Youzhong; Konoplev, Sergej; Sougnez, Carrie; Brown, Jennifer R.; Abruzzo, Lynne V.; Carter, Scott L.; Keating, Michael J.; Davids, Matthew S.; Wierda, William G.; Cibulskis, Kristian; Zenz, Thorsten; Werner, Lillian; Cin, Paola Dal; Kharchencko, Peter; Neuberg, Donna; Kantarjian, Hagop; Lander, Eric; Gabriel, Stacey; O'Brien, Susan; Letai, Anthony; Weitz, David A.; Nowak, Martin A.; Getz, Gad; Wu, Catherine J. (Nature Publishing Group, 2016)
      Resistance to the Bruton's tyrosine kinase (BTK) inhibitor ibrutinib has been attributed solely to mutations in BTK and related pathway molecules. Using whole-exome and deep-targeted sequencing, we dissect evolution of ...
    • Cloning and Sequencing of a Form II Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase from the Bacterial Symbiont of the Hydrothermal Vent Tubeworm Riftia pachyptila 

      Robinson, Jonathan J; Stein, Jeffrey L; Cavanaugh, Colleen Marie (American Society for Microbiology, 1998)
      The bacterial symbiont of the hydrothermal vent tubeworm fixes carbon via the Calvin-Benson cycle and has been shown previously to express a form II ribulose-1,5-bisphosphate carboxylase/oxygenase (RubisCO). The gene cbbM, ...
    • Cloning, Characterisation and Comparative Analysis of a Starch Synthase IV Gene in Wheat: Functional and Evolutionary Implications 

      Leterrier, Marina; Holappa, Lynn D; Broglie, Karen E; Beckles, Diane M (BioMed Central, 2008)
      Background: Starch is of great importance to humans as a food and biomaterial, and the amount and structure of starch made in plants is determined in part by starch synthase (SS) activity. Five SS isoforms, SSI, II, III, ...
    • A close call: does the location of incision at cesarean delivery matter in patients with vasa previa? A case report. 

      Neuhausser, Werner M; Baxi, Laxmi V (F1000Research, 2013)
      We present here a case of vasa previa in a multipara, diagnosed at the time of her late second trimester ultrasonogram. The patient subsequently underwent an elective cesarean section after 37 weeks gestation, giving birth ...
    • Closed String Tachyon Condensation at c =1 

      Karczmarek, Joanna L.; Strominger, Andrew (Springer Verlag, 2004)
      The c=1 matrix model, with or without a type 0 hat, has an exact quantum solution corresponding to closed string tachyon condensation along a null surface. The condensation occurs, and spacetime dissolves, at a finite ...
    • Closely overlapping responses to tools and hands in left lateral occipitotemporal cortex 

      Bracci, S.; Cavina-Pratesi, C.; Ietswaart, M.; Caramazza, Alfonso; Peelen, M. V. (American Physiological Society, 2011)
      The perception of object-directed actions performed by either hands or tools recruits regions in left fronto-parietal cortex. Here, using functional MRI (fMRI), we tested whether the common role of hands and tools in object ...