Now showing items 8254-8273 of 24540

    • FKBP12-Rapamycin-associated Protein (FRAP) Autophosphorylates at Serine 2481 under Translationally Repressive Conditions 

      Peterson, Randall T.; Beal, Peter A.; Comb, Michael J.; Schreiber, Stuart L. (American Society for Biochemistry and Molecular Biology, 2000)
      The FKBP12-rapamycin associated protein (FRAP, also RAFT, mTOR) belongs to a family of phosphatidylinositol kinase-related kinases, These kinases mediate cellular responses to stresses such as DNA damage and nutrient ...
    • FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction 

      Desai, Bimal N.; Myers, Benjamin R.; Schreiber, Stuart L. (National Academy of Sciences, 2002)
      FKBP12-rapamycin associated protein (FRAP, also known as mTOR or RAFT) is the founding member of the phosphatidylinositol kinase-related kinase family and functions as a sensor of physiological signals that regulate cell ...
    • Flagellar Biosynthesis in E.coli Is Regulated by a Cascade of Stochastic Pulses 

      Kim, Jeongho Mark (2017-01-20)
      Genetically identical populations of bacteria can exhibit significant phenotypic heterogeneity even in the absence of environmental variations. In bacteria such as Bacillus and Salmonella, flagellar motility has been found ...
    • Flagellar dynamics of a connected chain of active, polar, Brownian particles 

      Chelakkot, R.; Gopinath, A.; Mahadevan, Lakshminarayanan; Hagan, Marianne L (The Royal Society, 2013)
      We show that active, self-propelled particles that are connected together to form a single chain that is anchored at one end can produce the graceful beating motions of flagella. Changing the boundary condition from a clamp ...
    • The flagellar motor of Caulobacter crescentus generates more torque when a cell swims backward 

      Lele, Pushkar P.; Roland, Thibault; Shrivastava, Abhishek; Chen, Yihao; Berg, Howard C. (2016)
      Caulobacter crescentus, a monotrichous bacterium, swims by rotating a single right-handed helical filament. CW motor rotation thrusts the cell forward 1, a mode of motility known as the pusher mode; CCW motor rotation pulls ...
    • Flames, Splashes and Microdroplets: A Mathematical Approach to Three Fluid Dynamics Problems 

      Chemama, Michael Leopold (2015-01-13)
      Three different problems in fluid mechanics are presented in this thesis. The first one deals with the mechanism behind the extinction of a flame by an alternating electric field. A simple model for the interaction between ...
    • The flare activity of Sagittarius A* 

      Eckart, A.; Baganoff, F. K.; Schödel, R.; Morris, M.; Genzel, R.; Bower, G. C.; Marrone, D.; Moran, James M.; Viehmann, T.; Bautz, M. W.; Brandt, W. N.; Garmire, G. P.; Ott, T.; Trippe, S.; Ricker, G. R.; Straubmeier, C.; Roberts, D. A.; Yusef-Zadeh, F.; Zhao, Jun-Hui; Rao, Ramprasad (EDP Sciences, 2006)
      Context. We report new simultaneous near-infrared/sub-millimeter/X-ray observations of the SgrA* counterpart associated with the massive 3–4×106M⊙ black hole at the Galactic Center. Aims. The main aim is to investigate the ...
    • Flash Caching on the Storage Client 

      Holland, David A.; Angelino, Elaine Lee; Wald, Gideon; Seltzer, Margo I. (USENIX Association, 2013)
      Flash memory has recently become popular as a caching medium. Most uses to date are on the storage server side. We investigate a different structure: flash as a cache on the client side of a networked storage environment. ...
    • Flash Force: A Visual History of Might, Right and Light 

      Canales, Jimena (Association of Neuroesthetics, Berlin, 2011)
    • Flash Memory: Photochemical Imprinting of Neuronal Action Potentials onto a Microbial Rhodopsin 

      Venkatachalam, Veena; Brinks, Daan; Maclaurin, Dougal; Hochbaum, Daniel; Kralj, Joel; Cohen, Adam E. (American Chemical Society, 2014)
      We developed a technique, “flash memory”, to record a photochemical imprint of the activity state—firing or not firing—of a neuron at a user-selected moment in time. The key element is an engineered microbial rhodopsin ...
    • Flask: Staged Functional Programming for Sensor Networks 

      Mainland, Geoffrey; Morrisett, John Gregory; Welsh, Matt (Association for Computer Machinery, 2008)
      Severely resource-constrained devices present a confounding challenge to the functional programmer: we are used to having powerful abstraction facilities at our fingertips, but how can we make use of these tools on a device ...
    • Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis 

      Miao, Ji; Ling, Alisha V.; Manthena, Praveen V.; Gearing, Mary E.; Graham, Mark J.; Crooke, Rosanne M.; Croce, Kevin J.; Esquejo, Ryan M.; Clish, Clary B.; Torrecilla, Esther; Vázquez, Gumersindo Fernández; Rubio, Miguel A.; Cabrerizo, Lucio; Barabash, Ana; Pernaute, Andrés Sánchez; Torres, Antonio J.; Vicent, David; Biddinger, Sudha B. (Nature Pub. Group, 2015)
      Despite the well-documented association between insulin resistance and cardiovascular disease, the key targets of insulin relevant to the development of cardiovascular disease are not known. Here, using non-biased profiling ...
    • Flavor Anarchy in a Randall-Sundrum Model with 5D Minimal Flavor Violation and a Low Kaluza-Klein Scale 

      Fitzpatrick, A.; Perez, Gilad; Randall, Lisa (American Physical Society, 2008)
      A variant of a warped extra dimension model is presented. It is based on 5D minimal flavor violation, in which the only sources of flavor breaking are two 5D anarchic Yukawa matrices. These matrices also control the bulk ...
    • Flaw sensitivity of highly stretchable materials 

      Chen, Chao; Wang, Zhengjin; Suo, Zhigang (Elsevier BV, 2017)
      Elastomers and gels can often deform multiple times their original length. The stretchability is insensitive to small cuts in the samples, but reduces markedly when the cuts are large. We show that this transition occurs ...
    • Flexibility in Incumbent Organizations 

      Takeda, Yusaku (2022-05-16)
      For decades, scholars have theorized structural and cognitive mechanisms of inertia that induce rigidity and stasis in organizations. These scholars have explored organizational capacities to reorient strategies and ...
    • Flexible bacterial immunity as a strategy for widespread protection against protein threats 

      Knecht, Abigail (2023-03-14)
      How bacteria interact with their neighbors can have a large impact on community structure through cooperative measures like biofilm formation or antagonistic ones like pathogen invasion. These communications are often ...
    • Flexible Cognitive Resources: Competitive Content Maps for Attention and Memory 

      Franconeri, Steven L.; Alvarez, George; Cavanagh, Patrick (Elsevier BV, 2013-03)
      The brain has finite processing resources so that, as tasks become harder, performance degrades. Where do the limits on these resources come from? We focus on a variety of capacity-limited buffers related to attention, ...
    • Flexible Genome Recoding Strategies for Exploring Codon Space in the Escherichia Coli Genome 

      Napolitano, Michael G. (2017-01-25)
      The degeneracy of the genetic code allows nucleic acids to encode amino acid identity as well as non-coding information for gene regulation and genome maintenance. This dual-nature allows for maximal information density ...
    • A Flexible High-Performance Lattice Boltzmann GPU Code for the Simulations of Fluid Flows in Complex Geometries 

      Bernaschi, Massimo; Fatica, Massimiliano; Melchionna, Simone; Succi, Sauro; Kaxiras, Efthimios (Wiley-Blackwell, 2010)
      We describe the porting of the Lattice Boltzmann component of MUPHY, a multi-physics/scale simulation software, to multiple graphics processing units using the Compute Unified Device Architecture. The novelty of this work ...
    • Flexible Indeterminate Factor-Based Asset Allocation 

      Blyth, Stephen James; Szigety, Mark Charles; Xia, Jake (Institutional Investor Journals, 2016)
      Asset allocation represents a fundamental strategic decision for every institutional investor. Though many asset allocation approaches have been recommended and implemented in various forms, each has its own strengths and ...