Browsing Faculty of Arts and Sciences by Keyword "Capsid"
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HIV-1 capsid engages nucleoporin NUP153 to promote viral nuclear entry
(2014-02-25)Lentiviruses can infect non-dividing cells, and various cellular nuclear transport proteins provide crucial functions for lentiviral nuclear entry and integration. Genome-wide small interfering RNA screens previously ... -
Viral and Host Determinants of Primate Lentivirus Restriction by Old World Primate TRIM5alpha Proteins
(2014-10-21)The host restriction factor TRIM5α mediates a post-entry, pre-integration block to retroviral infection that depends upon recognition of the viral capsid by the TRIM5α PRYSPRY domain. The two predominant alleles of rhesus ...