Browsing Faculty of Arts and Sciences by Keyword "Cell Biology of Disease"
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FUS is sequestered in nuclear aggregates in ALS patient fibroblasts
(The American Society for Cell Biology, 2014)Mutations in the RNA-binding protein FUS have been shown to cause the neurodegenerative disease amyotrophic lateral sclerosis (ALS). We investigate whether mutant FUS protein in ALS patient–derived fibroblasts affects ...