Browsing Faculty of Arts and Sciences by Keyword "Cell cycle"
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The Cell Cycle and Differentiation in Stem Cells
(2013-03-08)The relationship between cellular proliferation and differentiation is a major topic in cell biology. What we know comes from models of somatic cell differentiation, where it is widely viewed that cycling and differentiation ... -
Small molecule inhibitors reveal novel functions of the APC/C through proteomic and chemical genetic screening
(2020-08-11)The Anaphase Promoting Complex/Cyclosome (APC/C) is a ~1.2 MDa ubiquitin ligase that controls the timing of the eukaryotic cell cycle by targeting key proteins for destruction by the 26S proteasome. During M-phase, the ...