Browsing Faculty of Arts and Sciences by Keyword "DNA origami"
Now showing items 1-4 of 4
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Coordination of Individual and Ensemble Cytoskeletal Motors Studied Using Tools from DNA Nanotechnology
(2013-09-30)The cytoskeletal molecular motors kinesin-1 and cytoplasmic dynein drive many diverse functions within eukaryotic cells. They are responsible for numerous spatially and temporally dependent intracellular processes crucial ... -
DNA Origami Nanoparticles for Cell Delivery: The Effect of Shape and Surface Functionalization on Cell Internalization
(2012-09-14)An outstanding challenge in modern medicine is the safe and efficient delivery of drugs. One approach to improve drug delivery yield and increase specificity towards diseased cells, is to employ a drug carrier to facilitate ... -
Investigating Cytoskeletal Motor Mechanisms using DNA Nanotechnology
(2014-02-25)The microtubule cytoskeleton plays a vital role in the spatial-temporal organization of subcellular cargo required to maintain homeostasis and direct cell division. Cytoplasmic dynein and kinesin are opposite-polarity, ... -
Tetrahedral expansion gel enables superior preservation of molecular structure for super-resolution imaging
(2021-11-16)Expansion microscopy (ExM) can increase the resolution of sub-diffraction microscopy methods such as stochastic optical reconstruction microscopy (STORM). However, it remains unknown to what extent ExM preserves structural ...