Browsing Faculty of Arts and Sciences by Keyword "High-throughput sequencing"
Now showing items 1-2 of 2
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False positives complicate ancient pathogen identifications using high-throughput shotgun sequencing
(BioMed Central, 2014)Background: Identification of historic pathogens is challenging since false positives and negatives are a serious risk. Environmental non-pathogenic contaminants are ubiquitous. Furthermore, public genetic databases contain ... -
Sort-seq under the hood: implications of design choices on large-scale characterization of sequence-function relations
(BioMed Central, 2016)Background: Sort-seq is an effective approach for simultaneous activity measurements in a large-scale library, combining flow cytometry, deep sequencing, and statistical inference. Such assays enable the characterization ...