Browsing Faculty of Arts and Sciences by Keyword "Motor Systems"

Now showing items 1-3 of 3

    • Agrin and Synaptic Laminin Are Required to Maintain Adult Neuromuscular Junctions 

      Samuel, Melanie Ann; Valdez, Gregorio; Tapia, Juan; Lichtman, Jeff; Sanes, Joshua R. (Public Library of Science, 2012)
      As synapses form and mature the synaptic partners produce organizing molecules that regulate each other’s differentiation and ensure precise apposition of pre- and post-synaptic specializations. At the skeletal neuromuscular ...

    • Monoaminergic Orchestration of Motor Programs in a Complex C. elegans Behavior 

      Donnelly, Jamie L.; Clark, Christopher M.; Leifer, Andrew M.; Pirri, Jennifer K.; Haburcak, Marian; Francis, Michael M.; Samuel, Aravinthan DT; Alkema, Mark J. (Public Library of Science, 2013)
      Monoamines provide chemical codes of behavioral states. However, the neural mechanisms of monoaminergic orchestration of behavior are poorly understood. Touch elicits an escape response in Caenorhabditis elegans where the ...

    • A Selective HDAC 1/2 Inhibitor Modulates Chromatin and Gene Expression in Brain and Alters Mouse Behavior in Two Mood-Related Tests 

      Schroeder, Frederick A.; Lewis, Michael C.; Fass, Daniel M.; Wagner, Florence F.; Zhang, Yan-Ling; Hennig, Krista M.; Gale, Jennifer; Zhao, Wen-Ning; Reis, Surya; Barker, Douglas D.; Berry-Scott, Erin; Kim, Sung Won; Clore, Elizabeth L.; Hooker, Jacob M.; Holson, Edward B.; Haggarty, Stephen J.; Petryshen, Tracey L. (Public Library of Science, 2013)
      Psychiatric diseases, including schizophrenia, bipolar disorder and major depression, are projected to lead global disease burden within the next decade. Pharmacotherapy, the primary – albeit often ineffective – treatment ...