Browsing Faculty of Arts and Sciences by Keyword "Structure"
Now showing items 1-3 of 3
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An affinity-structure database of helix-turn-helix: DNA complexes with a universal coordinate system
(BioMed Central, 2015)Background: Molecular interactions between proteins and DNA molecules underlie many cellular processes, including transcriptional regulation, chromosome replication, and nucleosome positioning. Computational analyses of ... -
Evidence for and Applications of Physics-Based Reasoning in AlphaFold
(2022-05-23)The problem of predicting a protein's 3D structure from its primary amino acid sequence is a longstanding challenge in structural biology. Recently, approaches like AlphaFold have achieved remarkable performance on this ... -
Structural Understanding of Remodeling Function of HIV-1 Reverse Transcriptase During Initiation
(2023-06-01)Reverse transcription in HIV-1 is initiated from an intermolecular template:primer duplex formed by annealing of the U5-primer binding site (U5-PBS) region of the HIV genome with a host tRNA. The structure of this RNA:RNA ...