Browsing Faculty of Arts and Sciences by Keyword "Vascular normalization"

Now showing items 1-1 of 1

    • Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy 

      Adapala, Ravi K.; Thoppil, Roslin J.; Ghosh, Kaustabh; Cappelli, Holly; Dudley, Andrew C.; Paruchuri, Sailaja; Keshamouni, Venkateshwar; Klagsbrun, Michael; Meszaros, J. Gary; Chilian, William M.; Ingber, Donald E.; Thodeti, Charles K. (2016)
      Tumor vessels are characterized by abnormal morphology and hyper-permeability that together cause inefficient delivery of chemotherapeutic agents. Although VEGF has been established as a critical regulator of tumor ...