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    • The Balance Between Mutators and Nonmutators in Asexual Populations 

      Desai, Michael M; Fisher, Daniel S. (Genetics Society of America, 2011)
      Mutator alleles, which elevate an individual’s mutation rate from 10 to 10,000-fold, have been found at high frequencies in many natural and ex- perimental populations. Mutators are continually produced from nonmu- tators, ...
    • Genetic Variation and the Fate of Beneficial Mutations in Asexual Populations 

      Lang, Gregory I.; Botstein, David; Desai, Michael M (Genetics Society of America, 2011)
      The fate of a newly arising beneficial mutation depends on many factors, such as the population size and the availability and fitness effects of other mutations that accumulate in the population. It has proven difficult ...