Browsing Faculty of Arts and Sciences by Keyword "cells"
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Cellular uptake mechanisms and endosomal trafficking of supercharged proteins
(Elsevier BV, 2012)Supercharged proteins can deliver functional macromolecules into the cytoplasm of mammalian cells with potencies that exceed those of cationic peptides. The structural features of supercharged proteins that determine their ... -
Epithelial Cells Derived from Human Embryonic Stem Cells Display P16INK4A Senescence, Hypermotility, and Differentiation Properties Shared by Many P63+ Somatic Cell Types
(Wiley-Blackwell, 2009)Human embryonic stem (hES) cells can generate cells expressing p63, K14, and involucrin, which have been proposed to be keratinocytes. Although these hES-derived, keratinocyte-like (hESderK) cells form epithelioid colonies ... -
Two Classes of Silencing RNAs Move between Caenorhabditis elegans Tissues
(Nature Publishing Group, a division of Macmillan Publishers Limited, 2011)Organism-wide RNA interference (RNAi) is due to the transport of mobile silencing RNA throughout the organism, but the identities of these mobile RNA species in animals are unknown. Here, we present genetic evidence that ...