Browsing Faculty of Arts and Sciences by Keyword "embryonic stem cells"

Now showing items 1-3 of 3

    • An Embryonic Stem Cell-Based System for Rapid Analysis of Transcriptional Enhancers 

      Tsanov, Kaloyan M; Nishi, Yuichi; Peterson, Kevin A; Liu, Jing; Baetscher, Manfred; McMahon, Andrew P. (Wiley Periodicals, Inc., 2012)
      With the growing use of genome-wide screens for cis-regulatory elements, there is a pressing need for platforms that enable fast and cost-effective experimental validation of identified hits in relevant developmental and ...

    • Genetic Targeting of the Endoderm with Claudin-6CreER 

      Anderson, William J.; Zhou, Qiao; Alcalde, Victor; Kaneko, Osamu F; Blank, Leah J; Sherwood, Richard Irving; Guseh, James Sawalla; Rajagopal, Jayaraj; Melton, Douglas A. (Wiley-Blackwell, 2008)
      A full description of the ontogeny of the β cell would guide efforts to generate β cells from embryonic stem cells (ESCs). The first step requires an understanding of definitive endoderm: the genes and signals responsible ...

    • Genome-wide Analysis of Ctcf-RNA Interactions 

      Kung, Johnny Tsun-Yi (2014-06-06)
      Ctcf is a "master regulator" of the genome that plays a role in a variety of gene regulatory functions as well as in genome architecture. Evidence from studying the epigenetic process of X-chromosome inactivation suggests ...