Browsing Faculty of Arts and Sciences by Keyword "AKT signaling cascade"

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    • Interleukin-6 Secretion by Astrocytes Is Dynamically Regulated by PI3K-mTOR-Calcium Signaling 

      Codeluppi, Simone; Fernandez-Zafra, Teresa; Sandor, Katalin; Kjell, Jacob; Liu, Qingsong; Abrams, Mathew; Olson, Lars; Gray, Nathanael S.; Svensson, Camilla I.; Uhlén, Per (Public Library of Science, 2014)
      After contusion spinal cord injury (SCI), astrocytes become reactive and form a glial scar. While this reduces spreading of the damage by containing the area of injury, it inhibits regeneration. One strategy to improve the ...