Browsing Faculty of Arts and Sciences by Keyword "Biology, Physiology"
Now showing items 1-8 of 8
-
The Biophysics of Vertebrate Hearing: A Single-Molecule Approach
(2015-05-22)Inner-ear mechanotransduction relies on tip links, fine protein filaments made of cadherin-23 and protocadherin-15 that convey tension to mechanosensitive channels at the tips of hair-cell stereocilia. The tip-link cadherins ... -
Foraging in a Complex World: From Individual Flight Performance to Collective Behavior in Bumblebees (Bombus Impatiens)
(2017-01-27)Foraging is a crucial and remarkably complex behavior that is key to survival. For social insects such as bumblebees, successful foraging depends on a combination of individual traits (e.g. physiological and biomechanical ... -
Mitochondrial Calcium Signaling in Brown Fat Bioenergetics
(2018-09-26)Calcium is a ubiquitous signaling molecule that coordinates biological processes over a wide range of length and timescales. For decades, it has been known that respiring mitochondria can take up large amounts of calcium ... -
Molecular mechanisms of metabolic adaptation to endurance exercise
(2018-08-31)Adaptation of cellular metabolism allows tissues to perform diverse, specialized functions. Endurance exercise training promotes aerobic oxidation of metabolic substrates in skeletal muscle by increasing mitochondrial ... -
Morphological, Physiological and Molecular Classification of Mouse Retinal Ganglion Cells
(2016-01-15)Visual information is conveyed from the retina to the brain through axons of retinal ganglion cells (RGCs). There are >20 different subtypes of RGCs, each of which detects specific features. Classification of RGC subtypes ... -
Predictive Pharmacokinetic Modeling of Orally Administered Drugs
(2016-06-22)Drug discovery and development is a long, costly process that could become more efficient if pre-clinical exploration of drugs was more thorough and accurate. In order to provide pre-clinical insight into drug absorption, ... -
The Regulation of Immunological Processes by Peripheral Neurons
(2015-09-23)The nervous system and the immune system are the primary sensory interfaces between the internal and external environment. They are responsible for recognizing, integrating, and responding to stimuli with the appropriate ... -
Targeted Measurement and Manipulation of Hydrogen Peroxide in the Cardiovascular System
(2017-08-24)Hydrogen peroxide (H2O2) is a reactive oxygen species (ROS) with a diverse range of reported roles in both normal physiology and disease. While H2O2 and other ROS have long been reported to be drivers of acute and chronic ...