Browsing Faculty of Arts and Sciences by Keyword "Chromothripsis"
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Chromothripsis as an On-Target Consequence of CRISPR–Cas9 Genome Editing
(2021-05-10)Genome editing has therapeutic potential for treating genetic diseases and cancer. However, the currently most practicable approaches rely on the generation of DNA double-strand breaks (DSBs), which can give rise to a ... -
The landscape of somatic mutations in primary prostate adenocarcinoma
(2013-10-08)Prostate cancer is the second leading cause of cancer deaths among men. Targeted analyses of DNA from prostate cancers have identified recurrent somatic alterations that promote tumor growth and survival. Only recently, ...