Browsing Faculty of Arts and Sciences by Keyword "Clonal Evolution"
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Defining and Targeting Transcriptional Pathways in Leukemia Stem Cells
(2014-10-21)Acute myeloid leukemia (AML) is a clonal neoplastic disorder organized as a cellular hierarchy, with the self-renewing leukemia stem cell (LSC) at the apex. Recurrent mutations in transcription factors (TF) and epigenetic ...