Browsing Faculty of Arts and Sciences by Keyword "Cytokine Receptors"

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    • Crystal Structure of the FERM-SH2 Module of Human Jak2 

      McNally, Randall; Toms, Angela V.; Eck, Michael J. (Public Library of Science, 2016)
      Jak-family tyrosine kinases mediate signaling from diverse cytokine receptors. Binding of Jaks to their cognate receptors is mediated by their N-terminal region, which contains FERM and SH2 domains. Here we describe the ...