Now showing items 1-6 of 6

    • Inter- and Intracellular Effects of Traumatic Axonal Injury 

      Dabiri, Borna Esfahani (2014-06-06)
      Mild Traumatic Brain Injuries (mTBIs) are non-penetrating brain injuries that do not result in gross pathological lesions, yet they may cause a spectrum of cognitive and behavioral deficits. mTBI has been placed in the ...
    • Mechanotransduction: the role of mechanical stress, myocyte shape, and cytoskeletal architecture on cardiac function 

      McCain, Megan L.; Parker, Kevin Kit (Springer Nature, 2011)
      Mechanotransduction refers to the conversion of mechanical forces into biochemical or electrical signals that initiate structural and functional remodeling in cells and tissues. The heart is a kinetic organ whose form ...
    • Molecular requirements for morphogenesis in Plasmodium falciparum, the human malaria parasite 

      Clements, Rebecca Lynn (2021-03-05)
      Malaria, which is caused by Plasmodium parasites, remains a major cause of illness and death worldwide. P. falciparum, the parasite responsible for severe malaria, alters its shape dramatically during development to adapt ...
    • A Possible Role for Integrin Signaling in Diffuse Axonal Injury 

      Hemphill, Matthew Allen; Dabiri, Borna Esfahani; Gabriele, Sylvain; Kerscher, Lucas; Franck, Christian; Goss, Josue; Alford, Patrick W.; Parker, Kevin Kit (Public Library of Science (PLoS), 2011)
      Over the past decade, investigators have attempted to establish the pathophysiological mechanisms by which non-penetrating injuries damage the brain. Several studies have implicated either membrane poration or ion channel ...
    • Self-Organization of Muscle Cell Structure and Function 

      Grosberg, Anna; Kuo, Po-Ling; Guo, Chin-Lin; Geisse, Nicholas A.; Bray, Mark-Anthony; Adams, William J.; Sheehy, Sean Paul; Parker, Kevin Kit (Public Library of Science (PLoS), 2011)
      The organization of muscle is the product of functional adaptation over several length scales spanning from the sarcomere to the muscle bundle. One possible strategy for solving this multiscale coupling problem is to ...
    • The Role and Regulation of FtsZ Filaments in Bacterial Cytokinesis 

      Squyres, Georgia Rae (2020-10-14)
      Like all cells, bacteria must divide in order to proliferate. This process must be carefully controlled in space and time to ensure that these cells maintain the appropriate size, shape, and DNA content, and respond ...