Browsing Faculty of Arts and Sciences by Keyword "bone"
Now showing items 1-3 of 3
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Applying Next Generation Sequencing to Skeletal Development and Disease
(2014-02-25)Next Generation Sequencing (NGS) technologies have dramatically increased the throughput and lowered the cost of DNA sequencing. In this thesis, I apply these technologies to unresolved questions in skeletal development ... -
Polycystin-1 and Bone Mechanotransduction
(2013-02-19)Bone mechanotransduction is a fundamental process underlying the remarkable ability of bones to perceive surrounding physical cues and adapt their mass, structure and overall strength to their mechanical environment. ... -
Variation in Estradiol Level Affects Cortical Bone Growth in Response to Mechanical Loading in Sheep
(The Company of Biologists, 2007)Although mechanical loading can stimulate cortical bone growth, little is known about how individual physiology affects this response. This study demonstrates that in vivo variation in estradiol (E2) level alters osteoblast ...