Now showing items 1-6 of 6
Harnessing Advances in Genomics and Molecular Genetics to Inform Understanding of P. vivax Epidemiology, Evolution, and Drug Resistance
Plasmodium vivax and Plasmodium falciparum are two parasites that cause most malaria cases worldwide. P. vivax is chronically understudied compared to P. falciparum, and significant aspects of its biology remain a mystery. ...
The Plastic and Adaptive Evolutionary Potential of Nonstructural Carbohydrates in a Temperate Tree Species
The ability to undergo plastic and evolutionary change in adaptive traits is key for plant survival under future climate change. Both processes require genetic variation in adaptive traits within populations. Thus, for my ...
In situ epigenomics across length scales
Chromatin is spatially organized across length scales, from DNA base pairs to chromosomes to tissues. This organization, which is encompassed in the term epigenomics, is thought to regulate gene expression and control ...
Phylogeography, color variation, and hybridization in an Andean tanager, Superciliaried Hemispingus (Aves: Thlypopsis superciliaris)
Natural history collections are invaluable libraries of Earth’s biodiversity. Museum specimens frequently span temporal, geographic, and taxonomic scales and afford unparalleled insights into environmental, organismal, and ...
A genomics love story: Tying the knot between micro- and macroevolution in the Mycobacterium tuberculosis complex
Tuberculosis (TB) is a leading cause of death globally. Understanding the population dynamics and evolution of TB’s causative agent Mycobacterium tuberculosis complex (MTBC) over short time-scales in-host (micro-evolution) ...
Somatic mutations in the human brain: Tracing the origins of cancer and schizophrenia
Somatic mutations, present in a subset of cells in the body, provide a unique opportunity for mechanistic understanding of disease. Somatic mutations represent natural experiments in humans akin to conditional transgenic ...