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Empirical Bayes Analysis of Quantitative Proteomics Experiments
(Public Library of Science, 2009)
Background: Advances in mass spectrometry-based proteomics have enabled the incorporation of proteomic data into systems approaches to biology. However, development of analytical methods has lagged behind. Here we describe ...
Single-Nucleosome Mapping of Histone Modifications in S. cerevisiae
(Public Library of Science, 2005)
Covalent modification of histone proteins plays a role in virtually every process on eukaryotic DNA, from transcription to DNA repair. Many different residues can be covalently modified, and it has been suggested that these ...