Now showing items 1-2 of 2
High-Resolution Mutation Mapping Reveals Parallel Experimental Evolution in Yeast
(Public Library of Science, 2006)
Understanding the genetic basis of evolutionary adaptation is limited by our ability to efficiently identify the genomic locations of adaptive mutations. Here we describe a method that can quickly and precisely map the ...
The Case for Selection at CCR5-Δ32
(Public Library of Science, 2005)
The C-C chemokine receptor 5, 32 base-pair deletion (CCR5-Δ32) allele confers strong resistance to infection by the AIDS virus HIV. Previous studies have suggested that CCR5-Δ32 arose within the past 1,000 y and rose to ...