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Statistical Methods for Analyzing DNA Methylation Data and Subpopulation Analysis of Continuous, Binary and Count Data for Clinical Trials
(2015-01-13)
DNA methylation may represent an important contributor to the missing heritability described in complex trait genetics. However, technology to measure DNA methylation has
outpaced statistical methods for analysis. Novel ...
Evolutionary Dynamics of a Multiple-Ploidy System in Arabidopsis Arenosa
(2015-05-18)
Whole-genome duplication (WGD), which leads to polyploidy, has been implicated in speciation and biological novelty. In plants, many species have experienced historical bouts of WGD or exhibit extant ploidy variation, which ...
Computational and Statistical Methods for Characterizing Single-Cell Heterogeneity
(2018-01-19)
The emergence of single-cell technologies has highlighted the potential to discover novel cellular subpopulations and states within heterogeneous populations. Such technologies are achieving increasingly higher-throughput, ...