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Optimization of Gene Expression by Natural Selection 

Bedford, Trevor; Hartl, Daniel L. (National Academy of Sciences, 2009)
It is generally assumed that stabilizing selection promoting a phenotypic optimum acts to shape variation in quantitative traits across individuals and species. Although gene expression represents an intensively studied ...
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Eukaryotic Organisms in Proterozoic Oceans 

Knoll, Andrew Herbert; Javaux, Emmanuelle J.; Hewitt, David; Cohen, Phoebe A (Royal Society, The, 2006)
The geological record of protists begins well before the Ediacaran and Cambrian diversification of animals, but the antiquity of that history, its reliability as a chronicle of evolution and the causal inferences that can ...
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Synergy and Discounting of Cooperation in Social Dilemmas 

Hauert, Christoph; Michor, Franziska; Nowak, Martin A.; Doebeli, Michael (Elsevier, 2006)
The emergence and maintenance of cooperation by natural selection is an enduring conundrum in evolutionary biology, which has been studied using a variety of game theoretical models inspired by different biological situations. ...
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Prelife Catalysts and Replicators 

Ohtsuki, Hisashi; Nowak, Martin A. (Royal Society, The, 2009)
Life is based on replication and evolution. But replication cannot be taken for granted. We must ask what there was prior to replication and evolution. How does evolution begin? We have proposed prelife as a generative ...
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Originator Dynamics 

Manapat, Michael L.; Ohtsuki, Hisashi; Bürger, Reinhard; Nowak, Martin A. (Elsevier, 2009)
We study the origin of evolution. Evolution is based on replication, mutation, and selection. But how does evolution begin? When do chemical kinetics turn into evolutionary dynamics? We propose “prelife” and “prevolution” ...

Direct Reciprocity with Costly Punishment: Generous Tit-for-Tat Prevails 

Rand, David Gertler; Ohtsuki, Hisashi; Nowak, Martin A. (Elsevier, 2009)
The standard model for direct reciprocity is the repeated Prisoner's Dilemma, where in each round players choose between cooperation and defection. Here we extend the standard framework to include costly punishment. Now ...

Recognizing and Interpreting the Fossils of Early Eukaryotes 

Javaux, Emmanuelle J.; Knoll, Andrew; Walter, Malcolm (Springer Verlag, 2003)
Using molecular sequence data, biologists can generate hypotheses of protistan phylogeny and divergence times. Fossils, however, provide our only direct constraints on the timing and environmental context of early eukaryotic ...

The Faculty of Language: What’s Special About It? 

Pinker, Steven; Jackendoff, Ray (Elsevier, 2005)
We examine the question of which aspects of language are uniquely human and uniquely linguistic in light of recent suggestions by Hauser, Chomsky, and Fitch that the only such aspect is syntactic recursion, the rest of ...
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Detective Work in the West Indies: Integrating Historical and Experimental Approaches to Study Island Lizard Evolution 

Losos, Jonathan (American Institute of Biological Sciences, 2007)
Evolutionary biology is a historical science, like astronomy and geology. Understanding how and why evolution has occurred requires synthesizing multiple lines of inquiry. Historical studies, such as those that estimate ...
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Burkholderia Xenovorans LB400 Harbors a Multi-Replicon, 9.73-Mbp Genome Shaped for Versatility 

Konstantinidis, Konstantinos T.; Seeger, Michael; Vergez, Lisa M.; Chain, Patrick S. G.; Malfatti, Stephanie A.; Denef, Vincent J.; Zhulin, Igor B.; Mahenthiralingam, Eshwar; LiPuma, John J.; Lao, Victoria; Larimer, Frank; Cordova, Macarena; Sul, Woo Jun; Tiedje, James M.; Spilker, Theodore; Land, Miriam; Tsoi, Tamara V.; Ulrich, Luke E.; Reyes, Valeria Latorre; Agullo, Loreine; Smith, Daryl; Parnell, J. Jacob; Ramette, Alban; Hauser, Loren; Richardson, Paul; Marx, Christopher; Gonzalez, Myriam; Gomez, Luis (National Academy of Sciences, 2006)
<i>Burkholderia xenovorans</i> LB400 (LB400), a well studied, effective polychlorinated biphenyl-degrader, has one of the two largest known bacterial genomes and is the first nonpathogenic <i>Burkholderia</i> isolate ...
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Keyword
  • evolution$:$ (23)
  • genomics (3)
  • bioinformatics (2)
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  • computational biology (2)
  • cooperation (2)
  • evolutionary dynamics (2)
  • gene therapy (2)
  • genetics (2)
  • origin of life (2)
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FAS Department
  • Organismic and Evolutionary Biology (13)
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  • Chemistry and Chemical Biology (1)
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