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Statistical methods for analyzing genetic sequencing association studies
Case-control genetic sequencing studies are increasingly being conducted to identify rare variants associated with complex diseases. Oftentimes, these studies collect a variety of secondary traits--quantitative and qualitative ...
Leveraging Functional Annotations and Multiethnic Data to Improve Polygenic Risk Prediction
Polygenic risk prediction is a widely-investigated topic because of its potential clinical application as well as its utility to have a better understanding of the genetic architecture of complex traits. Methods to perform ...