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Molecular Evolution in Rapidly Evolving Populations
Advances in DNA sequencing are creating new opportunities for studying the process of evolution. These measurements can be particularly useful for rapidly evolving microbial organisms, whose small size and fast generation ...
Epistasis and Pleiotropy in Evolving Populations
In the era of high-throughput genome sequencing, it has become possible to measure the genetic changes that drive evolution. These direct observations enable us to test both qualitative and quantitative hypotheses about ...
Genetic Draft and Linked Selection in Rapidly Adapting Populations
Evolution proceeds by the stochastic emergence and fixation of mutations over time. The dynamics of this process are well understood if beneficial mutations are sufficiently rare or the population is sufficiently small. ...