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dc.contributor.authorBetel, Doron
dc.contributor.authorWilson, Manda
dc.contributor.authorGabow, Aaron
dc.contributor.authorMarks, Debora S.
dc.contributor.authorSander, Chris
dc.date.accessioned2013-01-24T18:13:58Z
dc.date.issued2008
dc.identifier.citationBetel, Doron, Manda Wilson, Aaron Gabow, Debora S. Marks, and Chris Sander. 2008. The microRNA.org resource: Targets and expression. Nucleic Acids Research 36(Suppl. 1): D149-D153.en_US
dc.identifier.issn0305-1048en_US
dc.identifier.issn1362-4962en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:10219362
dc.description.abstractMicroRNA.org (http://www.microrna.org) is a comprehensive resource of microRNA target predictions and expression profiles. Target predictions are based on a development of the miRanda algorithm which incorporates current biological knowledge on target rules and on the use of an up-to-date compendium of mammalian microRNAs. MicroRNA expression profiles are derived from a comprehensive sequencing project of a large set of mammalian tissues and cell lines of normal and disease origin. Using an improved graphical interface, a user can explore (i) the set of genes that are potentially regulated by a particular microRNA, (ii) the implied cooperativity of multiple microRNAs on a particular mRNA and (iii) microRNA expression profiles in various tissues. To facilitate future updates and development, the microRNA.org database structure and software architecture is flexibly designed to incorporate new expression and target discoveries. The web resource provides users with functional information about the growing number of microRNAs and their interaction with target genes in many species and facilitates novel discoveries in microRNA gene regulation.en_US
dc.language.isoen_USen_US
dc.publisherOxford University Pressen_US
dc.relation.isversionofdoi:10.1093/nar/gkm995en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238905en_US
dash.licenseLAA
dc.titleThe MicroRNA.org Resource: Targets and Expressionen_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalNucleic Acids Researchen_US
dash.depositing.authorMarks, Debora S.
dc.date.available2013-01-24T18:13:58Z
dash.affiliation.otherHMS^Systems Biologyen_US
dc.identifier.doi10.1093/nar/gkm995*
dash.contributor.affiliatedMarks, Debora


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